Model Information	
Data Set	WORK.LONG	
Distribution	Negative Binomial	
Link Function	Log	
Dependent Variable	ndr	
Offset Variable	offset	

Number of Observations Read	4904	
Number of Observations Used	4712	
Missing Values	192	

Class Level Information	
Class	Levels	Values	
ID_COMB	1226	1383 1382 1380 1379 1378 1377 1376 1375 1374 1373 1371 1370 1369 1368 1367 1366 1365 1364 1363 1361 1360 1359 1358 1357 1355 1354 1353 1352 1351 1350 1349 1347 1346 1345 1344 1343 1342 1341 1339 1338 1337 1336 1335 1334 1333 1332 1331 1329 1328 1327 ...	
ABSTINENT	2	1 0	
NALTREXONE	2	1 0	
THERAPY	2	1 0	
month	4	4 3 2 1	

Parameter Information	
Parameter	Effect	ABSTINENT	NALTREXONE	THERAPY	month	
Prm1	Intercept					
Prm2	ABSTINENT	1				
Prm3	ABSTINENT	0				
Prm4	NALTREXONE		1			
Prm5	NALTREXONE		0			
Prm6	ABSTINENT*NALTREXONE	1	1			
Prm7	ABSTINENT*NALTREXONE	1	0			
Prm8	ABSTINENT*NALTREXONE	0	1			
Prm9	ABSTINENT*NALTREXONE	0	0			
Prm10	THERAPY			1		
Prm11	THERAPY			0		
Prm12	ABSTINENT*THERAPY	1		1		
Prm13	ABSTINENT*THERAPY	1		0		
Prm14	ABSTINENT*THERAPY	0		1		
Prm15	ABSTINENT*THERAPY	0		0		
Prm16	NALTREXONE*THERAPY		1	1		
Prm17	NALTREXONE*THERAPY		1	0		
Prm18	NALTREXONE*THERAPY		0	1		
Prm19	NALTREXONE*THERAPY		0	0		
Prm20	ABSTIN*NALTRE*THERAP	1	1	1		
Prm21	ABSTIN*NALTRE*THERAP	1	1	0		
Prm22	ABSTIN*NALTRE*THERAP	1	0	1		
Prm23	ABSTIN*NALTRE*THERAP	1	0	0		
Prm24	ABSTIN*NALTRE*THERAP	0	1	1		
Prm25	ABSTIN*NALTRE*THERAP	0	1	0		
Prm26	ABSTIN*NALTRE*THERAP	0	0	1		
Prm27	ABSTIN*NALTRE*THERAP	0	0	0		
Prm28	month				4	
Prm29	month				3	
Prm30	month				2	
Prm31	month				1	
Prm32	ABSTINENT*month	1			4	
Prm33	ABSTINENT*month	1			3	
Prm34	ABSTINENT*month	1			2	
Prm35	ABSTINENT*month	1			1	
Prm36	ABSTINENT*month	0			4	
Prm37	ABSTINENT*month	0			3	
Prm38	ABSTINENT*month	0			2	
Prm39	ABSTINENT*month	0			1	
Prm40	NALTREXONE*month		1		4	
Prm41	NALTREXONE*month		1		3	
Prm42	NALTREXONE*month		1		2	
Prm43	NALTREXONE*month		1		1	
Prm44	NALTREXONE*month		0		4	
Prm45	NALTREXONE*month		0		3	
Prm46	NALTREXONE*month		0		2	
Prm47	NALTREXONE*month		0		1	
Prm48	ABSTIN*NALTREX*month	1	1		4	
Prm49	ABSTIN*NALTREX*month	1	1		3	
Prm50	ABSTIN*NALTREX*month	1	1		2	
Prm51	ABSTIN*NALTREX*month	1	1		1	
Prm52	ABSTIN*NALTREX*month	1	0		4	
Prm53	ABSTIN*NALTREX*month	1	0		3	
Prm54	ABSTIN*NALTREX*month	1	0		2	
Prm55	ABSTIN*NALTREX*month	1	0		1	
Prm56	ABSTIN*NALTREX*month	0	1		4	
Prm57	ABSTIN*NALTREX*month	0	1		3	
Prm58	ABSTIN*NALTREX*month	0	1		2	
Prm59	ABSTIN*NALTREX*month	0	1		1	
Prm60	ABSTIN*NALTREX*month	0	0		4	
Prm61	ABSTIN*NALTREX*month	0	0		3	
Prm62	ABSTIN*NALTREX*month	0	0		2	
Prm63	ABSTIN*NALTREX*month	0	0		1	
Prm64	THERAPY*month			1	4	
Prm65	THERAPY*month			1	3	
Prm66	THERAPY*month			1	2	
Prm67	THERAPY*month			1	1	
Prm68	THERAPY*month			0	4	
Prm69	THERAPY*month			0	3	
Prm70	THERAPY*month			0	2	
Prm71	THERAPY*month			0	1	
Prm72	ABSTIN*THERAPY*month	1		1	4	
Prm73	ABSTIN*THERAPY*month	1		1	3	
Prm74	ABSTIN*THERAPY*month	1		1	2	
Prm75	ABSTIN*THERAPY*month	1		1	1	
Prm76	ABSTIN*THERAPY*month	1		0	4	
Prm77	ABSTIN*THERAPY*month	1		0	3	
Prm78	ABSTIN*THERAPY*month	1		0	2	
Prm79	ABSTIN*THERAPY*month	1		0	1	
Prm80	ABSTIN*THERAPY*month	0		1	4	
Prm81	ABSTIN*THERAPY*month	0		1	3	
Prm82	ABSTIN*THERAPY*month	0		1	2	
Prm83	ABSTIN*THERAPY*month	0		1	1	
Prm84	ABSTIN*THERAPY*month	0		0	4	
Prm85	ABSTIN*THERAPY*month	0		0	3	
Prm86	ABSTIN*THERAPY*month	0		0	2	
Prm87	ABSTIN*THERAPY*month	0		0	1	
Prm88	NALTRE*THERAPY*month		1	1	4	
Prm89	NALTRE*THERAPY*month		1	1	3	
Prm90	NALTRE*THERAPY*month		1	1	2	
Prm91	NALTRE*THERAPY*month		1	1	1	
Prm92	NALTRE*THERAPY*month		1	0	4	
Prm93	NALTRE*THERAPY*month		1	0	3	
Prm94	NALTRE*THERAPY*month		1	0	2	
Prm95	NALTRE*THERAPY*month		1	0	1	
Prm96	NALTRE*THERAPY*month		0	1	4	
Prm97	NALTRE*THERAPY*month		0	1	3	
Prm98	NALTRE*THERAPY*month		0	1	2	
Prm99	NALTRE*THERAPY*month		0	1	1	
Prm100	NALTRE*THERAPY*month		0	0	4	
Prm101	NALTRE*THERAPY*month		0	0	3	
Prm102	NALTRE*THERAPY*month		0	0	2	
Prm103	NALTRE*THERAPY*month		0	0	1	
Prm104	ABST*NALT*THER*month	1	1	1	4	
Prm105	ABST*NALT*THER*month	1	1	1	3	
Prm106	ABST*NALT*THER*month	1	1	1	2	
Prm107	ABST*NALT*THER*month	1	1	1	1	
Prm108	ABST*NALT*THER*month	1	1	0	4	
Prm109	ABST*NALT*THER*month	1	1	0	3	
Prm110	ABST*NALT*THER*month	1	1	0	2	
Prm111	ABST*NALT*THER*month	1	1	0	1	
Prm112	ABST*NALT*THER*month	1	0	1	4	
Prm113	ABST*NALT*THER*month	1	0	1	3	
Prm114	ABST*NALT*THER*month	1	0	1	2	
Prm115	ABST*NALT*THER*month	1	0	1	1	
Prm116	ABST*NALT*THER*month	1	0	0	4	
Prm117	ABST*NALT*THER*month	1	0	0	3	
Prm118	ABST*NALT*THER*month	1	0	0	2	
Prm119	ABST*NALT*THER*month	1	0	0	1	
Prm120	ABST*NALT*THER*month	0	1	1	4	
Prm121	ABST*NALT*THER*month	0	1	1	3	
Prm122	ABST*NALT*THER*month	0	1	1	2	
Prm123	ABST*NALT*THER*month	0	1	1	1	
Prm124	ABST*NALT*THER*month	0	1	0	4	
Prm125	ABST*NALT*THER*month	0	1	0	3	
Prm126	ABST*NALT*THER*month	0	1	0	2	
Prm127	ABST*NALT*THER*month	0	1	0	1	
Prm128	ABST*NALT*THER*month	0	0	1	4	
Prm129	ABST*NALT*THER*month	0	0	1	3	
Prm130	ABST*NALT*THER*month	0	0	1	2	
Prm131	ABST*NALT*THER*month	0	0	1	1	
Prm132	ABST*NALT*THER*month	0	0	0	4	
Prm133	ABST*NALT*THER*month	0	0	0	3	
Prm134	ABST*NALT*THER*month	0	0	0	2	
Prm135	ABST*NALT*THER*month	0	0	0	1	

Algorithm converged.	

GEE Model Information	
Correlation Structure	Unstructured	
Subject Effect	ID_COMB (1226 levels)	
Number of Clusters	1226	
Clusters With Missing Values	80	
Correlation Matrix Dimension	4	
Maximum Cluster Size	4	
Minimum Cluster Size	0	

Algorithm converged.	

GEE Fit Criteria	
QIC	-154324.6826	
QICu	-154326.6086	

Analysis Of GEE Parameter Estimates	
Empirical Standard Error Estimates	
Parameter		Estimate	Standard Error	95% Confidence Limits	Z	Pr > |Z|	
Intercept					-1.3547	0.0781	-1.5078	-1.2017	-17.35	<.0001	
ABSTINENT	1				-0.5408	0.1559	-0.8464	-0.2352	-3.47	0.0005	
ABSTINENT	0				0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE	1				-0.2796	0.1185	-0.5119	-0.0472	-2.36	0.0184	
NALTREXONE	0				0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*NALTREXONE	1	1			0.2932	0.2355	-0.1682	0.7547	1.25	0.2130	
ABSTINENT*NALTREXONE	1	0			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*NALTREXONE	0	1			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*NALTREXONE	0	0			0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY	1				-0.0990	0.1138	-0.3220	0.1240	-0.87	0.3842	
THERAPY	0				0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*THERAPY	1	1			-0.1465	0.2400	-0.6170	0.3240	-0.61	0.5416	
ABSTINENT*THERAPY	1	0			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*THERAPY	0	1			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*THERAPY	0	0			0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*THERAPY	1	1			0.3914	0.1655	0.0670	0.7159	2.36	0.0180	
NALTREXONE*THERAPY	1	0			0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*THERAPY	0	1			0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*THERAPY	0	0			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTRE*THERAP	1	1	1		-0.2180	0.3341	-0.8728	0.4367	-0.65	0.5139	
ABSTIN*NALTRE*THERAP	1	1	0		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTRE*THERAP	1	0	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTRE*THERAP	1	0	0		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTRE*THERAP	0	1	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTRE*THERAP	0	1	0		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTRE*THERAP	0	0	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTRE*THERAP	0	0	0		0.0000	0.0000	0.0000	0.0000	.	.	
month	4				0.3121	0.0584	0.1976	0.4267	5.34	<.0001	
month	3				0.2552	0.0528	0.1518	0.3587	4.84	<.0001	
month	2				0.1923	0.0449	0.1043	0.2803	4.28	<.0001	
month	1				0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*month	1	4			-0.0492	0.1573	-0.3575	0.2592	-0.31	0.7547	
ABSTINENT*month	1	3			0.0577	0.1252	-0.1877	0.3031	0.46	0.6449	
ABSTINENT*month	1	2			0.1035	0.1014	-0.0953	0.3023	1.02	0.3075	
ABSTINENT*month	1	1			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*month	0	4			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*month	0	3			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*month	0	2			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*month	0	1			0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*month	1	4			-0.0958	0.1004	-0.2926	0.1009	-0.95	0.3397	
NALTREXONE*month	1	3			-0.0830	0.0916	-0.2625	0.0966	-0.91	0.3651	
NALTREXONE*month	1	2			-0.0011	0.0728	-0.1437	0.1416	-0.01	0.9884	
NALTREXONE*month	1	1			0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*month	0	4			0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*month	0	3			0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*month	0	2			0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*month	0	1			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	1	1	4		0.1441	0.2224	-0.2917	0.5799	0.65	0.5169	
ABSTIN*NALTREX*month	1	1	3		0.1525	0.2032	-0.2458	0.5508	0.75	0.4530	
ABSTIN*NALTREX*month	1	1	2		-0.0430	0.1754	-0.3867	0.3008	-0.25	0.8064	
ABSTIN*NALTREX*month	1	1	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	1	0	4		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	1	0	3		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	1	0	2		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	1	0	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	0	1	4		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	0	1	3		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	0	1	2		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	0	1	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	0	0	4		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	0	0	3		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	0	0	2		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*NALTREX*month	0	0	1		0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	1	4			-0.1109	0.0925	-0.2922	0.0705	-1.20	0.2308	
THERAPY*month	1	3			-0.0851	0.0847	-0.2512	0.0810	-1.00	0.3152	
THERAPY*month	1	2			-0.0304	0.0655	-0.1588	0.0980	-0.46	0.6427	
THERAPY*month	1	1			0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	0	4			0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	0	3			0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	0	2			0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	0	1			0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	1	1	4		-0.1633	0.2165	-0.5877	0.2610	-0.75	0.4506	
ABSTIN*THERAPY*month	1	1	3		-0.2663	0.2025	-0.6631	0.1306	-1.32	0.1885	
ABSTIN*THERAPY*month	1	1	2		-0.1811	0.1569	-0.4887	0.1265	-1.15	0.2485	
ABSTIN*THERAPY*month	1	1	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	1	0	4		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	1	0	3		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	1	0	2		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	1	0	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	0	1	4		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	0	1	3		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	0	1	2		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	0	1	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	0	0	4		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	0	0	3		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	0	0	2		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTIN*THERAPY*month	0	0	1		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	1	1	4		-0.0802	0.1390	-0.3526	0.1921	-0.58	0.5636	
NALTRE*THERAPY*month	1	1	3		-0.0493	0.1289	-0.3020	0.2035	-0.38	0.7024	
NALTRE*THERAPY*month	1	1	2		-0.0830	0.0979	-0.2749	0.1089	-0.85	0.3964	
NALTRE*THERAPY*month	1	1	1		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	1	0	4		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	1	0	3		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	1	0	2		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	1	0	1		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	0	1	4		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	0	1	3		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	0	1	2		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	0	1	1		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	0	0	4		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	0	0	3		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	0	0	2		0.0000	0.0000	0.0000	0.0000	.	.	
NALTRE*THERAPY*month	0	0	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	1	1	4	-0.1003	0.3350	-0.7570	0.5563	-0.30	0.7646	
ABST*NALT*THER*month	1	1	1	3	-0.0743	0.3040	-0.6701	0.5215	-0.24	0.8069	
ABST*NALT*THER*month	1	1	1	2	0.0666	0.2352	-0.3943	0.5276	0.28	0.7770	
ABST*NALT*THER*month	1	1	1	1	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	1	0	4	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	1	0	3	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	1	0	2	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	1	0	1	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	0	1	4	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	0	1	3	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	0	1	2	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	0	1	1	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	0	0	4	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	0	0	3	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	0	0	2	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	1	0	0	1	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	1	1	4	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	1	1	3	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	1	1	2	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	1	1	1	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	1	0	4	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	1	0	3	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	1	0	2	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	1	0	1	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	0	1	4	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	0	1	3	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	0	1	2	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	0	1	1	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	0	0	4	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	0	0	3	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	0	0	2	0.0000	0.0000	0.0000	0.0000	.	.	
ABST*NALT*THER*month	0	0	0	1	0.0000	0.0000	0.0000	0.0000	.	.	

Score Statistics For Type 3 GEE Analysis	
Source	DF	Chi-Square	Pr > ChiSq	
ABSTINENT	1	53.02	<.0001	
NALTREXONE	1	0.24	0.6264	
ABSTINENT*NALTREXONE	1	2.22	0.1364	
THERAPY	1	6.19	0.0128	
ABSTINENT*THERAPY	1	7.04	0.0079	
NALTREXONE*THERAPY	1	1.91	0.1672	
ABSTIN*NALTRE*THERAP	1	0.60	0.4391	
month	3	26.75	<.0001	
ABSTINENT*month	3	1.53	0.6765	
NALTREXONE*month	3	1.40	0.7053	
ABSTIN*NALTREX*month	3	1.04	0.7909	
THERAPY*month	3	12.64	0.0055	
ABSTIN*THERAPY*month	3	4.00	0.2614	
NALTRE*THERAPY*month	3	0.62	0.8910	
ABST*NALT*THER*month	3	0.39	0.9426	

Model Information	
Data Set	WORK.LONG	
Distribution	Negative Binomial	
Link Function	Log	
Dependent Variable	ndr	
Offset Variable	offset	

Number of Observations Read	4904	
Number of Observations Used	4712	
Missing Values	192	

Class Level Information	
Class	Levels	Values	
ID_COMB	1226	1383 1382 1380 1379 1378 1377 1376 1375 1374 1373 1371 1370 1369 1368 1367 1366 1365 1364 1363 1361 1360 1359 1358 1357 1355 1354 1353 1352 1351 1350 1349 1347 1346 1345 1344 1343 1342 1341 1339 1338 1337 1336 1335 1334 1333 1332 1331 1329 1328 1327 ...	
ABSTINENT	2	1 0	
NALTREXONE	2	1 0	
THERAPY	2	1 0	
month	4	4 3 2 1	

Parameter Information	
Parameter	Effect	ABSTINENT	NALTREXONE	THERAPY	month	
Prm1	Intercept					
Prm2	ABSTINENT	1				
Prm3	ABSTINENT	0				
Prm4	NALTREXONE		1			
Prm5	NALTREXONE		0			
Prm6	THERAPY			1		
Prm7	THERAPY			0		
Prm8	month				4	
Prm9	month				3	
Prm10	month				2	
Prm11	month				1	
Prm12	ABSTINENT*THERAPY	1		1		
Prm13	ABSTINENT*THERAPY	1		0		
Prm14	ABSTINENT*THERAPY	0		1		
Prm15	ABSTINENT*THERAPY	0		0		
Prm16	THERAPY*month			1	4	
Prm17	THERAPY*month			1	3	
Prm18	THERAPY*month			1	2	
Prm19	THERAPY*month			1	1	
Prm20	THERAPY*month			0	4	
Prm21	THERAPY*month			0	3	
Prm22	THERAPY*month			0	2	
Prm23	THERAPY*month			0	1	
Prm24	NALTREXONE*THERAPY		1	1		
Prm25	NALTREXONE*THERAPY		1	0		
Prm26	NALTREXONE*THERAPY		0	1		
Prm27	NALTREXONE*THERAPY		0	0		

Algorithm converged.	

GEE Model Information	
Correlation Structure	Unstructured	
Subject Effect	ID_COMB (1226 levels)	
Number of Clusters	1226	
Clusters With Missing Values	80	
Correlation Matrix Dimension	4	
Maximum Cluster Size	4	
Minimum Cluster Size	0	

Algorithm converged.	

GEE Fit Criteria	
QIC	-155650.5637	
QICu	-155668.0416	

Analysis Of GEE Parameter Estimates	
Empirical Standard Error Estimates	
Parameter		Estimate	Standard Error	95% Confidence Limits	Z	Pr > |Z|	
Intercept			-1.3876	0.0725	-1.5296	-1.2456	-19.15	<.0001	
ABSTINENT	1		-0.3468	0.1084	-0.5593	-0.1342	-3.20	0.0014	
ABSTINENT	0		0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE	1		-0.2326	0.0926	-0.4141	-0.0511	-2.51	0.0120	
NALTREXONE	0		0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY	1		-0.0123	0.1016	-0.2113	0.1868	-0.12	0.9040	
THERAPY	0		0.0000	0.0000	0.0000	0.0000	.	.	
month	4		0.2726	0.0444	0.1856	0.3595	6.14	<.0001	
month	3		0.2520	0.0415	0.1706	0.3333	6.07	<.0001	
month	2		0.2121	0.0344	0.1447	0.2794	6.17	<.0001	
month	1		0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*THERAPY	1	1	-0.3935	0.1561	-0.6994	-0.0875	-2.52	0.0117	
ABSTINENT*THERAPY	1	0	0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*THERAPY	0	1	0.0000	0.0000	0.0000	0.0000	.	.	
ABSTINENT*THERAPY	0	0	0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	1	4	-0.2037	0.0633	-0.3278	-0.0796	-3.22	0.0013	
THERAPY*month	1	3	-0.1884	0.0591	-0.3043	-0.0726	-3.19	0.0014	
THERAPY*month	1	2	-0.1094	0.0456	-0.1988	-0.0200	-2.40	0.0165	
THERAPY*month	1	1	0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	0	4	0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	0	3	0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	0	2	0.0000	0.0000	0.0000	0.0000	.	.	
THERAPY*month	0	1	0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*THERAPY	1	1	0.2828	0.1302	0.0277	0.5379	2.17	0.0298	
NALTREXONE*THERAPY	1	0	0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*THERAPY	0	1	0.0000	0.0000	0.0000	0.0000	.	.	
NALTREXONE*THERAPY	0	0	0.0000	0.0000	0.0000	0.0000	.	.	

Score Statistics For Type 3 GEE Analysis	
Source	DF	Chi-Square	Pr > ChiSq	
ABSTINENT	1	52.96	<.0001	
NALTREXONE	1	1.94	0.1640	
THERAPY	1	5.78	0.0162	
month	3	46.99	<.0001	
ABSTINENT*THERAPY	1	6.05	0.0139	
THERAPY*month	3	11.13	0.0110	
NALTREXONE*THERAPY	1	4.68	0.0306	

ABSTINENT*THERAPY Least Squares Means	
ABSTINENT	THERAPY	Estimate	Standard Error	z Value	Pr > |z|	Alpha	Lower	Upper	Mean	Standard Error of Mean	
1	1	-2.0562	0.09987	-20.59	<.0001	0.05	-2.2519	-1.8604	0.1279	0.01278	
1	0	-1.6665	0.09531	-17.49	<.0001	0.05	-1.8533	-1.4797	0.1889	0.01800	
0	1	-1.3160	0.05159	-25.51	<.0001	0.05	-1.4171	-1.2148	0.2682	0.01384	
0	0	-1.3197	0.05330	-24.76	<.0001	0.05	-1.4242	-1.2152	0.2672	0.01424	

ABSTINENT*THERAPY Least Squares Means	
ABSTINENT	THERAPY	Lower Mean	Upper Mean	Exponentiated	Exponentiated Lower	Exponentiated Upper	
1	1	0.1052	0.1556	0.1279	0.1052	0.1556	
1	0	0.1567	0.2277	0.1889	0.1567	0.2277	
0	1	0.2424	0.2968	0.2682	0.2424	0.2968	
0	0	0.2407	0.2966	0.2672	0.2407	0.2966	

Differences of ABSTINENT*THERAPY Least Squares Means	
ABSTINENT	THERAPY	_ABSTINENT	_THERAPY	Estimate	Standard Error	z Value	Pr > |z|	Alpha	Lower	Upper	
1	1	1	0	-0.3897	0.1380	-2.82	0.0048	0.05	-0.6603	-0.1191	
1	1	0	1	-0.7402	0.1123	-6.59	<.0001	0.05	-0.9603	-0.5201	
1	1	0	0	-0.7365	0.1132	-6.51	<.0001	0.05	-0.9583	-0.5146	
1	0	0	1	-0.3505	0.1084	-3.23	0.0012	0.05	-0.5629	-0.1381	
1	0	0	0	-0.3468	0.1084	-3.20	0.0014	0.05	-0.5593	-0.1342	
0	1	0	0	0.003761	0.07418	0.05	0.9596	0.05	-0.1416	0.1492	

Differences of ABSTINENT*THERAPY Least Squares Means	
ABSTINENT	THERAPY	_ABSTINENT	_THERAPY	Exponentiated	Exponentiated Lower	Exponentiated Upper	
1	1	1	0	0.6773	0.5167	0.8877	
1	1	0	1	0.4770	0.3828	0.5945	
1	1	0	0	0.4788	0.3835	0.5977	
1	0	0	1	0.7043	0.5695	0.8710	
1	0	0	0	0.7070	0.5716	0.8744	
0	1	0	0	1.0038	0.8679	1.1609