Class Level Information	
Class	Levels	Values	
Treatment_group	4	1.Naltrexone + CBI 2.Naltrexone 3.CBI 4.Neither	

Number of Observations Read	721	
Number of Observations Used	721	

Source	DF	Sum of Squares	Mean Square	F Value	Pr > F	
Model	3	6.0253119	2.0084373	3.34	0.0189	
Error	717	431.0806211	0.6012282			
Corrected Total	720	437.1059330				

R-Square	Coeff Var	Root MSE	ldpd Mean	
0.013785	71.38636	0.775389	1.086187	

Source	DF	Type I SS	Mean Square	F Value	Pr > F	
Treatment_group	3	6.02531193	2.00843731	3.34	0.0189	

Source	DF	Type III SS	Mean Square	F Value	Pr > F	
Treatment_group	3	6.02531193	2.00843731	3.34	0.0189	

Treatment_group	ldpd LSMEAN	Standard Error	Pr > |t|	LSMEAN Number	
1.Naltrexone + CBI	1.04179294	0.05929548	<.0001	1	
2.Naltrexone	1.04066247	0.06018186	<.0001	2	
3.CBI	1.00911463	0.05731841	<.0001	3	
4.Neither	1.23172118	0.05469173	<.0001	4	

Least Squares Means for effect Treatment_group
Pr > |t| for H0: LSMean(i)=LSMean(j)

Dependent Variable: ldpd	
i/j	1	2	3	4	
1		0.9893	0.6920	0.0188	
2	0.9893		0.7044	0.0191	
3	0.6920	0.7044		0.0051	
4	0.0188	0.0191	0.0051		

Treatment_group	ldpd LSMEAN	95% Confidence Limits	
1.Naltrexone + CBI	1.041793	0.925379	1.158206	
2.Naltrexone	1.040662	0.922509	1.158816	
3.CBI	1.009115	0.896583	1.121647	
4.Neither	1.231721	1.124346	1.339096	

Least Squares Means for Effect Treatment_group	
i	j	Difference Between Means	95% Confidence Limits for LSMean(i)-LSMean(j)	
1	2	0.001130	-0.164738	0.166999	
1	3	0.032678	-0.129234	0.194590	
1	4	-0.189928	-0.348300	-0.031557	
2	3	0.031548	-0.131620	0.194716	
2	4	-0.191059	-0.350714	-0.031404	
3	4	-0.222607	-0.378147	-0.067066	

Note:	To ensure overall protection level, only probabilities associated with pre-planned comparisons should be used.	

Class Level Information	
Class	Levels	Values	
Treatment_group	4	1.Naltrexone + CBI 2.Naltrexone 3.CBI 4.Neither	

Number of Observations Read	721	
Number of Observations Used	721	

Source	DF	Sum of Squares	Mean Square	F Value	Pr > F	
Model	4	37.3828858	9.3457214	16.74	<.0001	
Error	716	399.7230472	0.5582724			
Corrected Total	720	437.1059330				

R-Square	Coeff Var	Root MSE	ldpd Mean	
0.085524	68.78895	0.747176	1.086187	

Source	DF	Type I SS	Mean Square	F Value	Pr > F	
ldpd0	1	29.63970010	29.63970010	53.09	<.0001	
Treatment_group	3	7.74318566	2.58106189	4.62	0.0033	

Source	DF	Type III SS	Mean Square	F Value	Pr > F	
ldpd0	1	31.35757383	31.35757383	56.17	<.0001	
Treatment_group	3	7.74318566	2.58106189	4.62	0.0033	

Treatment_group	ldpd LSMEAN	Standard Error	Pr > |t|	LSMEAN Number	
1.Naltrexone + CBI	1.03655665	0.05714227	<.0001	1	
2.Naltrexone	1.06011770	0.05805020	<.0001	2	
3.CBI	0.97995188	0.05536976	<.0001	3	
4.Neither	1.24665960	0.05273943	<.0001	4	

Least Squares Means for effect Treatment_group
Pr > |t| for H0: LSMean(i)=LSMean(j)

Dependent Variable: ldpd	
i/j	1	2	3	4	
1		0.7725	0.4769	0.0071	
2	0.7725		0.3187	0.0176	
3	0.4769	0.3187		0.0005	
4	0.0071	0.0176	0.0005		

Treatment_group	ldpd LSMEAN	95% Confidence Limits	
1.Naltrexone + CBI	1.036557	0.924370	1.148743	
2.Naltrexone	1.060118	0.946149	1.174087	
3.CBI	0.979952	0.871245	1.088658	
4.Neither	1.246660	1.143117	1.350202	

Least Squares Means for Effect Treatment_group	
i	j	Difference Between Means	95% Confidence Limits for LSMean(i)-LSMean(j)	
1	2	-0.023561	-0.183526	0.136404	
1	3	0.056605	-0.099542	0.212752	
1	4	-0.210103	-0.362804	-0.057402	
2	3	0.080166	-0.077580	0.237912	
2	4	-0.186542	-0.340393	-0.032691	
3	4	-0.266708	-0.417034	-0.116382	

Note:	To ensure overall protection level, only probabilities associated with pre-planned comparisons should be used.	

Class Level Information	
Class	Levels	Values	
Treatment_group	4	1.Naltrexone + CBI 2.Naltrexone 3.CBI 4.Neither	

Number of Observations Read	721	
Number of Observations Used	721	

Source	DF	Sum of Squares	Mean Square	F Value	Pr > F	
Model	3	1.8507187	0.6169062	2.04	0.1065	
Error	717	216.5366729	0.3020037			
Corrected Total	720	218.3873916				

R-Square	Coeff Var	Root MSE	ldpd0 Mean	
0.008474	25.89642	0.549549	2.122103	

Source	DF	Type I SS	Mean Square	F Value	Pr > F	
Treatment_group	3	1.85071872	0.61690624	2.04	0.1065	

Source	DF	Type III SS	Mean Square	F Value	Pr > F	
Treatment_group	3	1.85071872	0.61690624	2.04	0.1065	

Number of Observations Read	721	
Number of Observations Used	721	

Source	DF	Sum of Squares	Mean Square	F Value	Pr > F	
Model	1	1119.27169	1119.27169	62.84	<.0001	
Error	719	12805.65699	17.81037			
Corrected Total	720	13924.92868				

R-Square	Coeff Var	Root MSE	dpd4 Mean	
0.080379	131.9214	4.220234	3.199052	

Source	DF	Type I SS	Mean Square	F Value	Pr > F	
T0_DPD2	1	1119.271692	1119.271692	62.84	<.0001	

Source	DF	Type III SS	Mean Square	F Value	Pr > F	
T0_DPD2	1	1119.271692	1119.271692	62.84	<.0001	

Parameter	Estimate	Standard Error	t Value	Pr > |t|	
Intercept	1.452537834	0.27062948	5.37	<.0001	
T0_DPD2	0.199256629	0.02513515	7.93	<.0001	

Number of Observations Read	721	
Number of Observations Used	721	

Source	DF	Sum of Squares	Mean Square	F Value	Pr > F	
Model	1	29.6397001	29.6397001	52.30	<.0001	
Error	719	407.4662329	0.5667124			
Corrected Total	720	437.1059330				

R-Square	Coeff Var	Root MSE	ldpd Mean	
0.067809	69.30698	0.752803	1.086187	

Source	DF	Type I SS	Mean Square	F Value	Pr > F	
ldpd0	1	29.63970010	29.63970010	52.30	<.0001	

Source	DF	Type III SS	Mean Square	F Value	Pr > F	
ldpd0	1	29.63970010	29.63970010	52.30	<.0001	

Parameter	Estimate	Standard Error	t Value	Pr > |t|	
Intercept	0.3043974593	0.11167842	2.73	0.0066	
ldpd0	0.3684029693	0.05094101	7.23	<.0001	

Class Level Information	
Class	Levels	Values	
Treatment_group	4	1.Naltrexone + CBI 2.Naltrexone 3.CBI 4.Neither	

Number of Observations Read	721	
Number of Observations Used	721	

Source	DF	Sum of Squares	Mean Square	F Value	Pr > F	
Model	8	891.411464	111.426433	200.46	<.0001	
Error	713	396.331139	0.555864			
Uncorrected Total	721	1287.742603				

R-Square	Coeff Var	Root MSE	ldpd Mean	
0.093284	68.64042	0.745563	1.086187	

Source	DF	Type I SS	Mean Square	F Value	Pr > F	
Treatment_group	4	856.6619819	214.1654955	385.28	<.0001	
ldpd0*Treatment_grou	4	34.7494820	8.6873705	15.63	<.0001	

Source	DF	Type III SS	Mean Square	F Value	Pr > F	
Treatment_group	4	5.38343591	1.34585898	2.42	0.0471	
ldpd0*Treatment_grou	4	34.74948202	8.68737050	15.63	<.0001	

Parameter	Estimate	Standard Error	t Value	Pr > |t|	
Treatment_group      1.Naltrexone + CBI	0.2329900960	0.22314954	1.04	0.2968	
Treatment_group      2.Naltrexone	0.6325406684	0.23116075	2.74	0.0064	
Treatment_group      3.CBI	0.2223367389	0.22524878	0.99	0.3239	
Treatment_group      4.Neither	0.0766201287	0.21037474	0.36	0.7158	
ldpd0*Treatment_grou 1.Naltrexone + CBI	0.3786772890	0.10100976	3.75	0.0002	
ldpd0*Treatment_grou 2.Naltrexone	0.1970671456	0.10806516	1.82	0.0686	
ldpd0*Treatment_grou 3.CBI	0.3578316809	0.09933072	3.60	0.0003	
ldpd0*Treatment_grou 4.Neither	0.5545777717	0.09779685	5.67	<.0001	

Class Level Information	
Class	Levels	Values	
Treatment_group	4	1.Naltrexone + CBI 2.Naltrexone 3.CBI 4.Neither	

Number of Observations Read	721	
Number of Observations Used	721	

Source	DF	Sum of Squares	Mean Square	F Value	Pr > F	
Model	7	40.7747939	5.8249706	10.48	<.0001	
Error	713	396.3311390	0.5558642			
Corrected Total	720	437.1059330				

R-Square	Coeff Var	Root MSE	ldpd Mean	
0.093284	68.64042	0.745563	1.086187	

Source	DF	Type I SS	Mean Square	F Value	Pr > F	
ldpd0	1	29.63970010	29.63970010	53.32	<.0001	
Treatment_group	3	7.74318566	2.58106189	4.64	0.0032	
ldpd0*Treatment_grou	3	3.39190818	1.13063606	2.03	0.1078	

Source	DF	Type III SS	Mean Square	F Value	Pr > F	
ldpd0	1	29.79816696	29.79816696	53.61	<.0001	
Treatment_group	3	1.87345200	0.62448400	1.12	0.3387	
ldpd0*Treatment_grou	3	3.39190818	1.13063606	2.03	0.1078	

Treatment_group	ldpd LSMEAN	Standard Error	Pr > |t|	LSMEAN Number	
1.Naltrexone + CBI	0.61166739	0.12811865	<.0001	1	
2.Naltrexone	0.82960781	0.12939580	<.0001	2	
3.CBI	0.58016842	0.13120792	<.0001	3	
4.Neither	0.63119790	0.11823752	<.0001	4	

Least Squares Means for effect Treatment_group
Pr > |t| for H0: LSMean(i)=LSMean(j)

Dependent Variable: ldpd	
i/j	1	2	3	4	
1		0.2318	0.8637	0.9108	
2	0.2318		0.1763	0.2580	
3	0.8637	0.1763		0.7727	
4	0.9108	0.2580	0.7727		

Treatment_group	ldpd LSMEAN	95% Confidence Limits	
1.Naltrexone + CBI	0.611667	0.360132	0.863202	
2.Naltrexone	0.829608	0.575565	1.083650	
3.CBI	0.580168	0.322568	0.837768	
4.Neither	0.631198	0.399063	0.863333	

Least Squares Means for Effect Treatment_group	
i	j	Difference Between Means	95% Confidence Limits for LSMean(i)-LSMean(j)	
1	2	-0.217940	-0.575442	0.139561	
1	3	0.031499	-0.328539	0.391537	
1	4	-0.019531	-0.361812	0.322751	
2	3	0.249439	-0.112355	0.611234	
2	4	0.198410	-0.145718	0.542538	
3	4	-0.051029	-0.397793	0.295734	

Note:	To ensure overall protection level, only probabilities associated with pre-planned comparisons should be used.	

Treatment_group	ldpd LSMEAN	Standard Error	Pr > |t|	LSMEAN Number	
1.Naltrexone + CBI	0.99034467	0.05864300	<.0001	1	
2.Naltrexone	1.02667496	0.05837305	<.0001	2	
3.CBI	0.93800010	0.05854234	<.0001	3	
4.Neither	1.18577567	0.05320846	<.0001	4	

Least Squares Means for effect Treatment_group
Pr > |t| for H0: LSMean(i)=LSMean(j)

Dependent Variable: ldpd	
i/j	1	2	3	4	
1		0.6607	0.5278	0.0138	
2	0.6607		0.2838	0.0444	
3	0.5278	0.2838		0.0018	
4	0.0138	0.0444	0.0018		

Treatment_group	ldpd LSMEAN	95% Confidence Limits	
1.Naltrexone + CBI	0.990345	0.875211	1.105478	
2.Naltrexone	1.026675	0.912071	1.141279	
3.CBI	0.938000	0.823064	1.052936	
4.Neither	1.185776	1.081312	1.290240	

Least Squares Means for Effect Treatment_group	
i	j	Difference Between Means	95% Confidence Limits for LSMean(i)-LSMean(j)	
1	2	-0.036330	-0.198779	0.126119	
1	3	0.052345	-0.110339	0.215028	
1	4	-0.195431	-0.350893	-0.039969	
2	3	0.088675	-0.073634	0.250984	
2	4	-0.159101	-0.314171	-0.004031	
3	4	-0.247776	-0.403091	-0.092460	

Note:	To ensure overall protection level, only probabilities associated with pre-planned comparisons should be used.	

Treatment_group	ldpd LSMEAN	Standard Error	Pr > |t|	LSMEAN Number	
1.Naltrexone + CBI	1.36902196	0.10425718	<.0001	1	
2.Naltrexone	1.22374211	0.11587799	<.0001	2	
3.CBI	1.29583178	0.09680948	<.0001	3	
4.Neither	1.74035344	0.10397411	<.0001	4	

Least Squares Means for effect Treatment_group
Pr > |t| for H0: LSMean(i)=LSMean(j)

Dependent Variable: ldpd	
i/j	1	2	3	4	
1		0.3516	0.6071	0.0119	
2	0.3516		0.6332	0.0010	
3	0.6071	0.6332		0.0018	
4	0.0119	0.0010	0.0018		

Treatment_group	ldpd LSMEAN	95% Confidence Limits	
1.Naltrexone + CBI	1.369022	1.164334	1.573710	
2.Naltrexone	1.223742	0.996239	1.451245	
3.CBI	1.295832	1.105766	1.485898	
4.Neither	1.740353	1.536221	1.944485	

Least Squares Means for Effect Treatment_group	
i	j	Difference Between Means	95% Confidence Limits for LSMean(i)-LSMean(j)	
1	2	0.145280	-0.160751	0.451310	
1	3	0.073190	-0.206134	0.352514	
1	4	-0.371331	-0.660411	-0.082252	
2	3	-0.072090	-0.368540	0.224360	
2	4	-0.516611	-0.822270	-0.210952	
3	4	-0.444522	-0.723439	-0.165604	

Note:	To ensure overall protection level, only probabilities associated with pre-planned comparisons should be used.	

Class Level Information	
Class	Levels	Values	
Treatment_group	4	1.Naltrexone + CBI 2.Naltrexone 3.CBI 4.Neither	

Number of Observations Read	721	
Number of Observations Used	721	

Source	DF	Sum of Squares	Mean Square	F Value	Pr > F	
Model	4	37.3828858	9.3457214	16.74	<.0001	
Error	716	399.7230472	0.5582724			
Corrected Total	720	437.1059330				

R-Square	Coeff Var	Root MSE	ldpd Mean	
0.085524	68.78895	0.747176	1.086187	

Source	DF	Type I SS	Mean Square	F Value	Pr > F	
ldpd0	1	29.63970010	29.63970010	53.09	<.0001	
Treatment_group	3	7.74318566	2.58106189	4.62	0.0033	

Source	DF	Type III SS	Mean Square	F Value	Pr > F	
ldpd0	1	31.35757383	31.35757383	56.17	<.0001	
Treatment_group	3	7.74318566	2.58106189	4.62	0.0033	

Treatment_group	ldpd LSMEAN	Standard Error	Pr > |t|	LSMEAN Number	
1.Naltrexone + CBI	1.03655665	0.05714227	<.0001	1	
2.Naltrexone	1.06011770	0.05805020	<.0001	2	
3.CBI	0.97995188	0.05536976	<.0001	3	
4.Neither	1.24665960	0.05273943	<.0001	4	

Least Squares Means for effect Treatment_group
Pr > |t| for H0: LSMean(i)=LSMean(j)

Dependent Variable: ldpd	
i/j	1	2	3	4	
1		0.7725	0.4769	0.0071	
2	0.7725		0.3187	0.0176	
3	0.4769	0.3187		0.0005	
4	0.0071	0.0176	0.0005		

Treatment_group	ldpd LSMEAN	95% Confidence Limits	
1.Naltrexone + CBI	1.036557	0.924370	1.148743	
2.Naltrexone	1.060118	0.946149	1.174087	
3.CBI	0.979952	0.871245	1.088658	
4.Neither	1.246660	1.143117	1.350202	

Least Squares Means for Effect Treatment_group	
i	j	Difference Between Means	95% Confidence Limits for LSMean(i)-LSMean(j)	
1	2	-0.023561	-0.183526	0.136404	
1	3	0.056605	-0.099542	0.212752	
1	4	-0.210103	-0.362804	-0.057402	
2	3	0.080166	-0.077580	0.237912	
2	4	-0.186542	-0.340393	-0.032691	
3	4	-0.266708	-0.417034	-0.116382	

Note:	To ensure overall protection level, only probabilities associated with pre-planned comparisons should be used.	

Model Information	
Data Set	WORK.LONG	
Dependent Variable	ldpd	
Covariance Structure	Unstructured	
Subject Effect	ID_COMB	
Estimation Method	REML	
Residual Variance Method	None	
Fixed Effects SE Method	Model-Based	
Degrees of Freedom Method	Between-Within	

Class Level Information	
Class	Levels	Values	
ID_COMB	954	2 4 5 6 7 8 10 11 12 14 16 17 18 19 20 21 22 23 27 28 29 30 33 35 37 38 40 41 42 43 44 46 48 49 51 52 54 56 58 61 63 64 65 66 68 69 70 71 72 73 74 76 78 79 80 86 87 88 89 92 93 94 95 97 98 100 101 104 105 109 110 113 114 115 118 119 121 122 123 124 125 126 127 128 130 131 132 135 136 137 139 140 141 143 144 145 146 147 148 149 150 151 155 156 157 158 159 160 161 163 164 165 166 167 168 169 170 171 173 174 175 178 179 181 182 183 186 190 191 192 193 194 195 196 197 198 199 200 201 202 204 205 206 208 209 211 214 216 217 218 220 222 224 228 229 231 232 233 235 236 237 238 239 240 241 242 244 245 246 247 249 250 251 253 255 257 258 259 261 262 263 265 266 268 269 270 271 274 275 277 278 282 283 284 287 289 290 291 292 293 295 296 299 300 301 303 304 306 307 309 310 311 313 314 315 316 318 319 320 321 322 324 325 327 328 329 330 332 333 334 335 336 338 340 341 342 343 345 346 347 349 350 351 352 353 354 356 357 358 359 360 361 363 364 365 366 367 369 371 372 374 376 379 380 382 383 384 385 386 388 390 392 394 396 397 400 401 402 404 405 406 407 408 409 410 411 413 414 415 416 417 419 420 421 422 423 424 426 428 429 430 431 432 433 435 437 438 440 442 443 444 445 447 449 450 452 453 455 457 458 459 460 462 463 465 467 468 469 470 472 474 476 480 481 482 483 484 485 487 490 492 493 494 496 497 498 499 501 502 504 505 506 507 509 511 512 520 522 525 526 527 528 529 530 531 533 534 538 542 543 545 546 548 550 551 554 555 556 557 559 560 564 565 567 571 575 577 580 581 586 587 588 591 592 593 594 595 598 601 602 604 605 606 607 608 609 610 611 612 614 615 618 619 622 624 626 628 629 630 631 633 634 635 636 637 639 640 642 643 645 646 649 650 651 652 654 655 661 665 666 667 668 670 671 672 675 676 677 679 680 682 685 687 688 689 691 694 695 696 697 698 700 701 703 704 706 708 709 710 711 713 714 715 717 720 721 723 724 725 726 728 729 731 732 733 735 737 738 739 740 741 742 743 745 749 750 751 752 753 756 757 758 759 761 763 765 767 768 770 771 773 774 775 776 777 778 780 782 783 786 788 790 792 794 795 796 797 799 802 803 804 806 807 808 809 810 811 812 814 818 819 820 822 823 824 826 827 828 830 831 832 834 835 836 837 839 841 842 844 845 846 847 849 850 852 854 855 856 857 860 861 862 863 864 865 866 868 869 872 873 874 875 876 877 878 879 881 882 883 886 887 888 889 890 891 892 895 896 897 898 899 901 902 903 904 905 906 908 909 910 911 913 914 915 917 918 919 920 921 922 923 924 926 927 930 931 932 933 934 935 937 938 939 940 941 943 944 945 947 948 949 950 951 953 954 955 956 957 958 959 960 962 963 964 966 967 968 969 970 971 972 974 975 976 978 979 980 981 982 983 984 986 987 988 990 991 992 994 995 996 997 998 999 1000 1001 1003 1005 1006 1007 1011 1012 1014 1015 1019 1020 1023 1024 1025 1026 1030 1031 1032 1033 1034 1035 1037 1038 1043 1045 1047 1048 1050 1051 1052 1053 1054 1057 1058 1059 1062 1063 1064 1065 1066 1067 1068 1069 1070 1071 1074 1075 1076 1077 1078 1081 1082 1083 1084 1087 1088 1089 1090 1091 1092 1093 1094 1095 1096 1097 1098 1099 1100 1101 1103 1104 1105 1106 1107 1108 1112 1115 1116 1117 1119 1120 1122 1124 1126 1127 1129 1130 1131 1133 1135 1137 1138 1139 1141 1142 1143 1144 1145 1146 1147 1148 1149 1150 1151 1152 1154 1156 1157 1158 1160 1162 1163 1164 1165 1166 1167 1168 1169 1170 1171 1173 1174 1175 1177 1179 1180 1181 1182 1183 1185 1186 1187 1188 1189 1191 1192 1193 1194 1195 1196 1197 1198 1199 1200 1201 1203 1204 1206 1207 1208 1209 1211 1212 1213 1214 1215 1216 1219 1220 1221 1222 1223 1224 1225 1227 1228 1229 1231 1232 1233 1234 1235 1236 1237 1239 1240 1241 1242 1244 1245 1246 1247 1248 1249 1251 1252 1255 1256 1257 1258 1259 1260 1261 1262 1263 1265 1266 1268 1269 1270 1273 1274 1275 1276 1279 1280 1281 1282 1284 1286 1288 1289 1290 1291 1294 1295 1298 1299 1300 1302 1303 1304 1305 1306 1307 1309 1310 1313 1315 1318 1320 1326 1327 1328 1331 1334 1337 1338 1339 1342 1343 1344 1346 1347 1349 1350 1351 1352 1353 1354 1357 1358 1359 1361 1363 1364 1365 1366 1367 1368 1369 1373 1374 1375 1376 1377 1378 1379 1380 1382	
Treatment_group	4	1.Naltrexone + CBI 2.Naltrexone 3.CBI 4.Neither	
month	4	1 2 3 4	

Dimensions	
Covariance Parameters	10	
Columns in X	50	
Columns in Z	0	
Subjects	954	
Max Obs per Subject	4	

Number of Observations	
Number of Observations Read	3004	
Number of Observations Used	3004	
Number of Observations Not Used	0	

Iteration History	
Iteration	Evaluations	-2 Res Log Like	Criterion	
0	1	6535.73879885		
1	2	4566.97733285	0.02118389	
2	1	4556.13866781	0.00150391	
3	1	4555.42036671	0.00001153	
4	1	4555.41511356	0.00000000	

Convergence criteria met.	

Covariance Parameter Estimates	
Cov Parm	Subject	Estimate	
UN(1,1)	ID_COMB	0.4223	
UN(2,1)	ID_COMB	0.3645	
UN(2,2)	ID_COMB	0.5354	
UN(3,1)	ID_COMB	0.2872	
UN(3,2)	ID_COMB	0.4160	
UN(3,3)	ID_COMB	0.5350	
UN(4,1)	ID_COMB	0.2784	
UN(4,2)	ID_COMB	0.4016	
UN(4,3)	ID_COMB	0.4547	
UN(4,4)	ID_COMB	0.5602	

Fit Statistics	
-2 Res Log Likelihood	4555.4	
AIC (Smaller is Better)	4575.4	
AICC (Smaller is Better)	4575.5	
BIC (Smaller is Better)	4624.0	

Null Model Likelihood Ratio Test	
DF	Chi-Square	Pr > ChiSq	
9	1980.32	<.0001	

Type 3 Tests of Fixed Effects	
Effect	Num DF	Den DF	F Value	Pr > F	
ldpd0	1	946	73.89	<.0001	
Treatment_group	3	946	1.57	0.1939	
ldpd0*Treatment_grou	3	946	2.44	0.0632	
month	3	946	0.65	0.5805	
ldpd0*month	3	946	0.60	0.6161	
Treatment_grou*month	9	946	1.75	0.0733	
ldpd0*Treatmen*month	9	946	2.12	0.0255	

Least Squares Means	
Effect	Treatment_group	month	ldpd0	Estimate	Standard Error	DF	t Value	Pr > |t|	Alpha	
Treatment_grou*month	1.Naltrexone + CBI	1	1.00	0.4544	0.09447	946	4.81	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	1.00	0.5644	0.1041	946	5.42	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	1.00	0.5329	0.1085	946	4.91	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	1.00	0.5767	0.1144	946	5.04	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	1	1.00	0.6155	0.1006	946	6.12	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	2	1.00	0.7019	0.1103	946	6.37	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	3	1.00	0.8371	0.1157	946	7.24	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	4	1.00	0.8390	0.1184	946	7.09	<.0001	0.05	
Treatment_grou*month	3.CBI	1	1.00	0.5868	0.09857	946	5.95	<.0001	0.05	
Treatment_grou*month	3.CBI	2	1.00	0.6591	0.1115	946	5.91	<.0001	0.05	
Treatment_grou*month	3.CBI	3	1.00	0.4298	0.1147	946	3.75	0.0002	0.05	
Treatment_grou*month	3.CBI	4	1.00	0.5383	0.1199	946	4.49	<.0001	0.05	
Treatment_grou*month	4.Neither	1	1.00	0.6362	0.09830	946	6.47	<.0001	0.05	
Treatment_grou*month	4.Neither	2	1.00	0.7050	0.1091	946	6.46	<.0001	0.05	
Treatment_grou*month	4.Neither	3	1.00	0.7030	0.1105	946	6.36	<.0001	0.05	
Treatment_grou*month	4.Neither	4	1.00	0.6068	0.1131	946	5.36	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.00	0.9382	0.04504	946	20.83	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.00	0.9702	0.05025	946	19.31	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.00	0.9559	0.05159	946	18.53	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.00	0.9626	0.05379	946	17.90	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	1	2.00	0.8129	0.04596	946	17.69	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	2	2.00	0.9090	0.05130	946	17.72	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	3	2.00	0.9606	0.05264	946	18.25	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	4	2.00	0.9406	0.05407	946	17.40	<.0001	0.05	
Treatment_grou*month	3.CBI	1	2.00	0.8347	0.04536	946	18.40	<.0001	0.05	
Treatment_grou*month	3.CBI	2	2.00	0.9202	0.05102	946	18.04	<.0001	0.05	
Treatment_grou*month	3.CBI	3	2.00	0.8600	0.05183	946	16.59	<.0001	0.05	
Treatment_grou*month	3.CBI	4	2.00	0.8915	0.05396	946	16.52	<.0001	0.05	
Treatment_grou*month	4.Neither	1	2.00	0.9040	0.04406	946	20.52	<.0001	0.05	
Treatment_grou*month	4.Neither	2	2.00	1.0452	0.04899	946	21.34	<.0001	0.05	
Treatment_grou*month	4.Neither	3	2.00	1.1044	0.04987	946	22.15	<.0001	0.05	
Treatment_grou*month	4.Neither	4	2.00	1.1315	0.05091	946	22.23	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.00	1.4219	0.08412	946	16.90	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.00	1.3760	0.08937	946	15.40	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.00	1.3789	0.09240	946	14.92	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.00	1.3486	0.09612	946	14.03	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	1	3.00	1.0103	0.08574	946	11.78	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	2	3.00	1.1161	0.09364	946	11.92	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	3	3.00	1.0841	0.09952	946	10.89	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	4	3.00	1.0421	0.1026	946	10.15	<.0001	0.05	
Treatment_grou*month	3.CBI	1	3.00	1.0827	0.08015	946	13.51	<.0001	0.05	
Treatment_grou*month	3.CBI	2	3.00	1.1812	0.08812	946	13.40	<.0001	0.05	
Treatment_grou*month	3.CBI	3	3.00	1.2902	0.08890	946	14.51	<.0001	0.05	
Treatment_grou*month	3.CBI	4	3.00	1.2446	0.09162	946	13.58	<.0001	0.05	
Treatment_grou*month	4.Neither	1	3.00	1.1719	0.08583	946	13.65	<.0001	0.05	
Treatment_grou*month	4.Neither	2	3.00	1.3855	0.09445	946	14.67	<.0001	0.05	
Treatment_grou*month	4.Neither	3	3.00	1.5059	0.09559	946	15.75	<.0001	0.05	
Treatment_grou*month	4.Neither	4	3.00	1.6562	0.09801	946	16.90	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.00	0.9382	0.04504	946	20.83	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.00	0.9702	0.05025	946	19.31	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.00	0.9559	0.05159	946	18.53	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.00	0.9626	0.05379	946	17.90	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	1	2.00	0.8129	0.04596	946	17.69	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	2	2.00	0.9090	0.05130	946	17.72	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	3	2.00	0.9606	0.05264	946	18.25	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	4	2.00	0.9406	0.05407	946	17.40	<.0001	0.05	
Treatment_grou*month	3.CBI	1	2.00	0.8347	0.04536	946	18.40	<.0001	0.05	
Treatment_grou*month	3.CBI	2	2.00	0.9202	0.05102	946	18.04	<.0001	0.05	
Treatment_grou*month	3.CBI	3	2.00	0.8600	0.05183	946	16.59	<.0001	0.05	
Treatment_grou*month	3.CBI	4	2.00	0.8915	0.05396	946	16.52	<.0001	0.05	
Treatment_grou*month	4.Neither	1	2.00	0.9040	0.04406	946	20.52	<.0001	0.05	
Treatment_grou*month	4.Neither	2	2.00	1.0452	0.04899	946	21.34	<.0001	0.05	
Treatment_grou*month	4.Neither	3	2.00	1.1044	0.04987	946	22.15	<.0001	0.05	
Treatment_grou*month	4.Neither	4	2.00	1.1315	0.05091	946	22.23	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.00	1.4219	0.08412	946	16.90	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.00	1.3760	0.08937	946	15.40	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.00	1.3789	0.09240	946	14.92	<.0001	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.00	1.3486	0.09612	946	14.03	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	1	3.00	1.0103	0.08574	946	11.78	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	2	3.00	1.1161	0.09364	946	11.92	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	3	3.00	1.0841	0.09952	946	10.89	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	4	3.00	1.0421	0.1026	946	10.15	<.0001	0.05	
Treatment_grou*month	3.CBI	1	3.00	1.0827	0.08015	946	13.51	<.0001	0.05	
Treatment_grou*month	3.CBI	2	3.00	1.1812	0.08812	946	13.40	<.0001	0.05	
Treatment_grou*month	3.CBI	3	3.00	1.2902	0.08890	946	14.51	<.0001	0.05	
Treatment_grou*month	3.CBI	4	3.00	1.2446	0.09162	946	13.58	<.0001	0.05	
Treatment_grou*month	4.Neither	1	3.00	1.1719	0.08583	946	13.65	<.0001	0.05	
Treatment_grou*month	4.Neither	2	3.00	1.3855	0.09445	946	14.67	<.0001	0.05	
Treatment_grou*month	4.Neither	3	3.00	1.5059	0.09559	946	15.75	<.0001	0.05	
Treatment_grou*month	4.Neither	4	3.00	1.6562	0.09801	946	16.90	<.0001	0.05	

Least Squares Means	
Effect	Treatment_group	month	Lower	Upper	
Treatment_grou*month	1.Naltrexone + CBI	1	0.2690	0.6398	
Treatment_grou*month	1.Naltrexone + CBI	2	0.3601	0.7686	
Treatment_grou*month	1.Naltrexone + CBI	3	0.3201	0.7458	
Treatment_grou*month	1.Naltrexone + CBI	4	0.3522	0.8011	
Treatment_grou*month	2.Naltrexone	1	0.4180	0.8130	
Treatment_grou*month	2.Naltrexone	2	0.4856	0.9183	
Treatment_grou*month	2.Naltrexone	3	0.6101	1.0641	
Treatment_grou*month	2.Naltrexone	4	0.6067	1.0714	
Treatment_grou*month	3.CBI	1	0.3934	0.7802	
Treatment_grou*month	3.CBI	2	0.4403	0.8780	
Treatment_grou*month	3.CBI	3	0.2046	0.6550	
Treatment_grou*month	3.CBI	4	0.3031	0.7736	
Treatment_grou*month	4.Neither	1	0.4432	0.8291	
Treatment_grou*month	4.Neither	2	0.4909	0.9192	
Treatment_grou*month	4.Neither	3	0.4861	0.9198	
Treatment_grou*month	4.Neither	4	0.3848	0.8288	
Treatment_grou*month	1.Naltrexone + CBI	1	0.8498	1.0266	
Treatment_grou*month	1.Naltrexone + CBI	2	0.8716	1.0688	
Treatment_grou*month	1.Naltrexone + CBI	3	0.8546	1.0571	
Treatment_grou*month	1.Naltrexone + CBI	4	0.8571	1.0682	
Treatment_grou*month	2.Naltrexone	1	0.7227	0.9031	
Treatment_grou*month	2.Naltrexone	2	0.8083	1.0097	
Treatment_grou*month	2.Naltrexone	3	0.8573	1.0639	
Treatment_grou*month	2.Naltrexone	4	0.8345	1.0467	
Treatment_grou*month	3.CBI	1	0.7457	0.9238	
Treatment_grou*month	3.CBI	2	0.8201	1.0203	
Treatment_grou*month	3.CBI	3	0.7583	0.9617	
Treatment_grou*month	3.CBI	4	0.7856	0.9974	
Treatment_grou*month	4.Neither	1	0.8176	0.9905	
Treatment_grou*month	4.Neither	2	0.9491	1.1414	
Treatment_grou*month	4.Neither	3	1.0066	1.2023	
Treatment_grou*month	4.Neither	4	1.0316	1.2314	
Treatment_grou*month	1.Naltrexone + CBI	1	1.2568	1.5869	
Treatment_grou*month	1.Naltrexone + CBI	2	1.2007	1.5514	
Treatment_grou*month	1.Naltrexone + CBI	3	1.1975	1.5602	
Treatment_grou*month	1.Naltrexone + CBI	4	1.1600	1.5373	
Treatment_grou*month	2.Naltrexone	1	0.8421	1.1786	
Treatment_grou*month	2.Naltrexone	2	0.9323	1.2998	
Treatment_grou*month	2.Naltrexone	3	0.8888	1.2794	
Treatment_grou*month	2.Naltrexone	4	0.8407	1.2435	
Treatment_grou*month	3.CBI	1	0.9254	1.2400	
Treatment_grou*month	3.CBI	2	1.0083	1.3542	
Treatment_grou*month	3.CBI	3	1.1157	1.4647	
Treatment_grou*month	3.CBI	4	1.0648	1.4244	
Treatment_grou*month	4.Neither	1	1.0034	1.3403	
Treatment_grou*month	4.Neither	2	1.2001	1.5708	
Treatment_grou*month	4.Neither	3	1.3183	1.6935	
Treatment_grou*month	4.Neither	4	1.4639	1.8485	
Treatment_grou*month	1.Naltrexone + CBI	1	0.8498	1.0266	
Treatment_grou*month	1.Naltrexone + CBI	2	0.8716	1.0688	
Treatment_grou*month	1.Naltrexone + CBI	3	0.8546	1.0571	
Treatment_grou*month	1.Naltrexone + CBI	4	0.8571	1.0682	
Treatment_grou*month	2.Naltrexone	1	0.7227	0.9031	
Treatment_grou*month	2.Naltrexone	2	0.8083	1.0097	
Treatment_grou*month	2.Naltrexone	3	0.8573	1.0639	
Treatment_grou*month	2.Naltrexone	4	0.8345	1.0467	
Treatment_grou*month	3.CBI	1	0.7457	0.9238	
Treatment_grou*month	3.CBI	2	0.8201	1.0203	
Treatment_grou*month	3.CBI	3	0.7583	0.9617	
Treatment_grou*month	3.CBI	4	0.7856	0.9974	
Treatment_grou*month	4.Neither	1	0.8176	0.9905	
Treatment_grou*month	4.Neither	2	0.9491	1.1414	
Treatment_grou*month	4.Neither	3	1.0066	1.2023	
Treatment_grou*month	4.Neither	4	1.0316	1.2314	
Treatment_grou*month	1.Naltrexone + CBI	1	1.2568	1.5869	
Treatment_grou*month	1.Naltrexone + CBI	2	1.2007	1.5514	
Treatment_grou*month	1.Naltrexone + CBI	3	1.1975	1.5602	
Treatment_grou*month	1.Naltrexone + CBI	4	1.1600	1.5373	
Treatment_grou*month	2.Naltrexone	1	0.8421	1.1786	
Treatment_grou*month	2.Naltrexone	2	0.9323	1.2998	
Treatment_grou*month	2.Naltrexone	3	0.8888	1.2794	
Treatment_grou*month	2.Naltrexone	4	0.8407	1.2435	
Treatment_grou*month	3.CBI	1	0.9254	1.2400	
Treatment_grou*month	3.CBI	2	1.0083	1.3542	
Treatment_grou*month	3.CBI	3	1.1157	1.4647	
Treatment_grou*month	3.CBI	4	1.0648	1.4244	
Treatment_grou*month	4.Neither	1	1.0034	1.3403	
Treatment_grou*month	4.Neither	2	1.2001	1.5708	
Treatment_grou*month	4.Neither	3	1.3183	1.6935	
Treatment_grou*month	4.Neither	4	1.4639	1.8485	

Differences of Least Squares Means	
Effect	Treatment_group	month	_Treatment_group	_month	ldpd0	Estimate	Standard Error	DF	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	2	2.00	-0.03206	0.03623	946	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	3	2.00	-0.01774	0.04675	946	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	4	2.00	-0.02449	0.05011	946	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	1	2.00	0.1252	0.06435	946	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	2	2.00	0.02915	0.06827	946	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	3	2.00	-0.02244	0.06928	946	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	4	2.00	-0.00242	0.07037	946	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	1	2.00	0.1034	0.06392	946	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	2	2.00	0.01798	0.06806	946	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	3	2.00	0.07817	0.06867	946	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	4	2.00	0.04669	0.07029	946	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	1	2.00	0.03414	0.06301	946	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	2	2.00	-0.1071	0.06655	946	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	3	2.00	-0.1663	0.06720	946	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	4	2.00	-0.1933	0.06797	946	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	3	2.00	0.01432	0.03746	946	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	4	2.00	0.007572	0.04247	946	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	1	2.00	0.1573	0.06810	946	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	2	2.00	0.06121	0.07181	946	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	3	2.00	0.009618	0.07278	946	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	4	2.00	0.02964	0.07382	946	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	1	2.00	0.1355	0.06770	946	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	2	2.00	0.05004	0.07161	946	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	3	2.00	0.1102	0.07220	946	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	4	2.00	0.07875	0.07373	946	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	1	2.00	0.06620	0.06683	946	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	2	2.00	-0.07503	0.07018	946	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	3	2.00	-0.1342	0.07080	946	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	4	2.00	-0.1613	0.07153	946	
Treatment_grou*month	1.Naltrexone + CBI	3	1.Naltrexone + CBI	4	2.00	-0.00675	0.03474	946	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	1	2.00	0.1430	0.06909	946	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	2	2.00	0.04689	0.07276	946	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	3	2.00	-0.00471	0.07371	946	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	4	2.00	0.01532	0.07473	946	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	1	2.00	0.1211	0.06869	946	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	2	2.00	0.03571	0.07255	946	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	3	2.00	0.09590	0.07313	946	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	4	2.00	0.06442	0.07465	946	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	1	2.00	0.05188	0.06784	946	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	2	2.00	-0.08935	0.07115	946	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	3	2.00	-0.1485	0.07175	946	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	4	2.00	-0.1756	0.07248	946	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	1	2.00	0.1497	0.07075	946	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	2	2.00	0.05364	0.07433	946	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	3	2.00	0.002046	0.07526	946	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	4	2.00	0.02207	0.07627	946	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	1	2.00	0.1279	0.07036	946	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	2	2.00	0.04247	0.07413	946	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	3	2.00	0.1027	0.07470	946	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	4	2.00	0.07118	0.07619	946	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	1	2.00	0.05863	0.06953	946	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	2	2.00	-0.08260	0.07275	946	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	3	2.00	-0.1418	0.07335	946	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	4	2.00	-0.1688	0.07406	946	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	2	2.00	-0.09608	0.03740	946	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	3	2.00	-0.1477	0.04793	946	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	4	2.00	-0.1277	0.05055	946	
Treatment_grou*month	2.Naltrexone	1	3.CBI	1	2.00	-0.02182	0.06457	946	
Treatment_grou*month	2.Naltrexone	1	3.CBI	2	2.00	-0.1073	0.06866	946	
Treatment_grou*month	2.Naltrexone	1	3.CBI	3	2.00	-0.04706	0.06927	946	
Treatment_grou*month	2.Naltrexone	1	3.CBI	4	2.00	-0.07854	0.07087	946	
Treatment_grou*month	2.Naltrexone	1	4.Neither	1	2.00	-0.09109	0.06366	946	
Treatment_grou*month	2.Naltrexone	1	4.Neither	2	2.00	-0.2323	0.06717	946	
Treatment_grou*month	2.Naltrexone	1	4.Neither	3	2.00	-0.2915	0.06782	946	
Treatment_grou*month	2.Naltrexone	1	4.Neither	4	2.00	-0.3186	0.06858	946	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	3	2.00	-0.05160	0.03889	946	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	4	2.00	-0.03157	0.04293	946	
Treatment_grou*month	2.Naltrexone	2	3.CBI	1	2.00	0.07426	0.06848	946	
Treatment_grou*month	2.Naltrexone	2	3.CBI	2	2.00	-0.01117	0.07235	946	
Treatment_grou*month	2.Naltrexone	2	3.CBI	3	2.00	0.04901	0.07293	946	
Treatment_grou*month	2.Naltrexone	2	3.CBI	4	2.00	0.01754	0.07445	946	
Treatment_grou*month	2.Naltrexone	2	4.Neither	1	2.00	0.004986	0.06762	946	
Treatment_grou*month	2.Naltrexone	2	4.Neither	2	2.00	-0.1362	0.07094	946	
Treatment_grou*month	2.Naltrexone	2	4.Neither	3	2.00	-0.1954	0.07155	946	
Treatment_grou*month	2.Naltrexone	2	4.Neither	4	2.00	-0.2225	0.07227	946	
Treatment_grou*month	2.Naltrexone	3	2.Naltrexone	4	2.00	0.02002	0.03577	946	
Treatment_grou*month	2.Naltrexone	3	3.CBI	1	2.00	0.1259	0.06949	946	
Treatment_grou*month	2.Naltrexone	3	3.CBI	2	2.00	0.04042	0.07331	946	
Treatment_grou*month	2.Naltrexone	3	3.CBI	3	2.00	0.1006	0.07388	946	
Treatment_grou*month	2.Naltrexone	3	3.CBI	4	2.00	0.06913	0.07538	946	
Treatment_grou*month	2.Naltrexone	3	4.Neither	1	2.00	0.05658	0.06865	946	
Treatment_grou*month	2.Naltrexone	3	4.Neither	2	2.00	-0.08465	0.07191	946	
Treatment_grou*month	2.Naltrexone	3	4.Neither	3	2.00	-0.1438	0.07251	946	
Treatment_grou*month	2.Naltrexone	3	4.Neither	4	2.00	-0.1709	0.07323	946	
Treatment_grou*month	2.Naltrexone	4	3.CBI	1	2.00	0.1058	0.07057	946	
Treatment_grou*month	2.Naltrexone	4	3.CBI	2	2.00	0.02040	0.07434	946	
Treatment_grou*month	2.Naltrexone	4	3.CBI	3	2.00	0.08059	0.07490	946	
Treatment_grou*month	2.Naltrexone	4	3.CBI	4	2.00	0.04911	0.07638	946	
Treatment_grou*month	2.Naltrexone	4	4.Neither	1	2.00	0.03656	0.06974	946	
Treatment_grou*month	2.Naltrexone	4	4.Neither	2	2.00	-0.1047	0.07296	946	
Treatment_grou*month	2.Naltrexone	4	4.Neither	3	2.00	-0.1639	0.07355	946	
Treatment_grou*month	2.Naltrexone	4	4.Neither	4	2.00	-0.1909	0.07426	946	
Treatment_grou*month	3.CBI	1	3.CBI	2	2.00	-0.08544	0.03721	946	
Treatment_grou*month	3.CBI	1	3.CBI	3	2.00	-0.02525	0.04715	946	
Treatment_grou*month	3.CBI	1	3.CBI	4	2.00	-0.05673	0.05047	946	
Treatment_grou*month	3.CBI	1	4.Neither	1	2.00	-0.06927	0.06323	946	
Treatment_grou*month	3.CBI	1	4.Neither	2	2.00	-0.2105	0.06676	946	
Treatment_grou*month	3.CBI	1	4.Neither	3	2.00	-0.2697	0.06741	946	
Treatment_grou*month	3.CBI	1	4.Neither	4	2.00	-0.2967	0.06818	946	
Treatment_grou*month	3.CBI	2	3.CBI	3	2.00	0.06019	0.03785	946	
Treatment_grou*month	3.CBI	2	3.CBI	4	2.00	0.02871	0.04267	946	
Treatment_grou*month	3.CBI	2	4.Neither	1	2.00	0.01616	0.06741	946	
Treatment_grou*month	3.CBI	2	4.Neither	2	2.00	-0.1251	0.07073	946	
Treatment_grou*month	3.CBI	2	4.Neither	3	2.00	-0.1843	0.07134	946	
Treatment_grou*month	3.CBI	2	4.Neither	4	2.00	-0.2113	0.07207	946	
Treatment_grou*month	3.CBI	3	3.CBI	4	2.00	-0.03148	0.03478	946	
Treatment_grou*month	3.CBI	3	4.Neither	1	2.00	-0.04403	0.06803	946	
Treatment_grou*month	3.CBI	3	4.Neither	2	2.00	-0.1853	0.07132	946	
Treatment_grou*month	3.CBI	3	4.Neither	3	2.00	-0.2444	0.07193	946	
Treatment_grou*month	3.CBI	3	4.Neither	4	2.00	-0.2715	0.07265	946	
Treatment_grou*month	3.CBI	4	4.Neither	1	2.00	-0.01255	0.06966	946	
Treatment_grou*month	3.CBI	4	4.Neither	2	2.00	-0.1538	0.07288	946	
Treatment_grou*month	3.CBI	4	4.Neither	3	2.00	-0.2130	0.07347	946	
Treatment_grou*month	3.CBI	4	4.Neither	4	2.00	-0.2400	0.07418	946	
Treatment_grou*month	4.Neither	1	4.Neither	2	2.00	-0.1412	0.03441	946	
Treatment_grou*month	4.Neither	1	4.Neither	3	2.00	-0.2004	0.04463	946	
Treatment_grou*month	4.Neither	1	4.Neither	4	2.00	-0.2275	0.04687	946	
Treatment_grou*month	4.Neither	2	4.Neither	3	2.00	-0.05919	0.03578	946	
Treatment_grou*month	4.Neither	2	4.Neither	4	2.00	-0.08624	0.03938	946	
Treatment_grou*month	4.Neither	3	4.Neither	4	2.00	-0.02705	0.03197	946	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	2	3.00	0.04582	0.07063	946	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	3	3.00	0.04301	0.08857	946	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	4	3.00	0.07323	0.09395	946	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	1	3.00	0.4116	0.1201	946	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	2	3.00	0.3058	0.1259	946	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	3	3.00	0.3378	0.1303	946	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	4	3.00	0.3797	0.1327	946	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	1	3.00	0.3392	0.1162	946	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	2	3.00	0.2406	0.1218	946	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	3	3.00	0.1317	0.1224	946	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	4	3.00	0.1772	0.1244	946	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	1	3.00	0.2500	0.1202	946	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	2	3.00	0.03641	0.1265	946	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	3	3.00	-0.08402	0.1273	946	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	4	3.00	-0.2343	0.1292	946	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	3	3.00	-0.00281	0.06768	946	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	4	3.00	0.02741	0.07613	946	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	1	3.00	0.3657	0.1238	946	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	2	3.00	0.2600	0.1294	946	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	3	3.00	0.2920	0.1338	946	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	4	3.00	0.3339	0.1361	946	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	1	3.00	0.2934	0.1200	946	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	2	3.00	0.1948	0.1255	946	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	3	3.00	0.08585	0.1261	946	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	4	3.00	0.1314	0.1280	946	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	1	3.00	0.2042	0.1239	946	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	2	3.00	-0.00942	0.1300	946	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	3	3.00	-0.1298	0.1309	946	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	4	3.00	-0.2801	0.1326	946	
Treatment_grou*month	1.Naltrexone + CBI	3	1.Naltrexone + CBI	4	3.00	0.03022	0.06103	946	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	1	3.00	0.3685	0.1261	946	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	2	3.00	0.2628	0.1316	946	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	3	3.00	0.2948	0.1358	946	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	4	3.00	0.3367	0.1381	946	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	1	3.00	0.2962	0.1223	946	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	2	3.00	0.1976	0.1277	946	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	3	3.00	0.08866	0.1282	946	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	4	3.00	0.1342	0.1301	946	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	1	3.00	0.2070	0.1261	946	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	2	3.00	-0.00661	0.1321	946	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	3	3.00	-0.1270	0.1329	946	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	4	3.00	-0.2773	0.1347	946	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	1	3.00	0.3383	0.1288	946	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	2	3.00	0.2326	0.1342	946	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	3	3.00	0.2646	0.1384	946	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	4	3.00	0.3065	0.1406	946	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	1	3.00	0.2660	0.1252	946	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	2	3.00	0.1674	0.1304	946	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	3	3.00	0.05844	0.1309	946	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	4	3.00	0.1040	0.1328	946	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	1	3.00	0.1768	0.1289	946	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	2	3.00	-0.03683	0.1348	946	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	3	3.00	-0.1573	0.1356	946	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	4	3.00	-0.3076	0.1373	946	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	2	3.00	-0.1058	0.07240	946	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	3	3.00	-0.07376	0.09547	946	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	4	3.00	-0.03181	0.1005	946	
Treatment_grou*month	2.Naltrexone	1	3.CBI	1	3.00	-0.07235	0.1174	946	
Treatment_grou*month	2.Naltrexone	1	3.CBI	2	3.00	-0.1709	0.1230	946	
Treatment_grou*month	2.Naltrexone	1	3.CBI	3	3.00	-0.2799	0.1235	946	
Treatment_grou*month	2.Naltrexone	1	3.CBI	4	3.00	-0.2343	0.1255	946	
Treatment_grou*month	2.Naltrexone	1	4.Neither	1	3.00	-0.1616	0.1213	946	
Treatment_grou*month	2.Naltrexone	1	4.Neither	2	3.00	-0.3751	0.1276	946	
Treatment_grou*month	2.Naltrexone	1	4.Neither	3	3.00	-0.4956	0.1284	946	
Treatment_grou*month	2.Naltrexone	1	4.Neither	4	3.00	-0.6459	0.1302	946	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	3	3.00	0.03201	0.07759	946	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	4	3.00	0.07396	0.08530	946	
Treatment_grou*month	2.Naltrexone	2	3.CBI	1	3.00	0.03341	0.1233	946	
Treatment_grou*month	2.Naltrexone	2	3.CBI	2	3.00	-0.06515	0.1286	946	
Treatment_grou*month	2.Naltrexone	2	3.CBI	3	3.00	-0.1741	0.1291	946	
Treatment_grou*month	2.Naltrexone	2	3.CBI	4	3.00	-0.1285	0.1310	946	
Treatment_grou*month	2.Naltrexone	2	4.Neither	1	3.00	-0.05579	0.1270	946	
Treatment_grou*month	2.Naltrexone	2	4.Neither	2	3.00	-0.2694	0.1330	946	
Treatment_grou*month	2.Naltrexone	2	4.Neither	3	3.00	-0.3898	0.1338	946	
Treatment_grou*month	2.Naltrexone	2	4.Neither	4	3.00	-0.5401	0.1356	946	
Treatment_grou*month	2.Naltrexone	3	2.Naltrexone	4	3.00	0.04195	0.07292	946	
Treatment_grou*month	2.Naltrexone	3	3.CBI	1	3.00	0.001403	0.1278	946	
Treatment_grou*month	2.Naltrexone	3	3.CBI	2	3.00	-0.09716	0.1329	946	
Treatment_grou*month	2.Naltrexone	3	3.CBI	3	3.00	-0.2061	0.1334	946	
Treatment_grou*month	2.Naltrexone	3	3.CBI	4	3.00	-0.1606	0.1353	946	
Treatment_grou*month	2.Naltrexone	3	4.Neither	1	3.00	-0.08780	0.1314	946	
Treatment_grou*month	2.Naltrexone	3	4.Neither	2	3.00	-0.3014	0.1372	946	
Treatment_grou*month	2.Naltrexone	3	4.Neither	3	3.00	-0.4218	0.1380	946	
Treatment_grou*month	2.Naltrexone	3	4.Neither	4	3.00	-0.5721	0.1397	946	
Treatment_grou*month	2.Naltrexone	4	3.CBI	1	3.00	-0.04055	0.1302	946	
Treatment_grou*month	2.Naltrexone	4	3.CBI	2	3.00	-0.1391	0.1353	946	
Treatment_grou*month	2.Naltrexone	4	3.CBI	3	3.00	-0.2481	0.1358	946	
Treatment_grou*month	2.Naltrexone	4	3.CBI	4	3.00	-0.2025	0.1376	946	
Treatment_grou*month	2.Naltrexone	4	4.Neither	1	3.00	-0.1298	0.1338	946	
Treatment_grou*month	2.Naltrexone	4	4.Neither	2	3.00	-0.3433	0.1395	946	
Treatment_grou*month	2.Naltrexone	4	4.Neither	3	3.00	-0.4638	0.1402	946	
Treatment_grou*month	2.Naltrexone	4	4.Neither	4	3.00	-0.6141	0.1419	946	
Treatment_grou*month	3.CBI	1	3.CBI	2	3.00	-0.09857	0.06386	946	
Treatment_grou*month	3.CBI	1	3.CBI	3	3.00	-0.2075	0.08108	946	
Treatment_grou*month	3.CBI	1	3.CBI	4	3.00	-0.1620	0.08571	946	
Treatment_grou*month	3.CBI	1	4.Neither	1	3.00	-0.08921	0.1174	946	
Treatment_grou*month	3.CBI	1	4.Neither	2	3.00	-0.3028	0.1239	946	
Treatment_grou*month	3.CBI	1	4.Neither	3	3.00	-0.4232	0.1247	946	
Treatment_grou*month	3.CBI	1	4.Neither	4	3.00	-0.5735	0.1266	946	
Treatment_grou*month	3.CBI	2	3.CBI	3	3.00	-0.1090	0.06390	946	
Treatment_grou*month	3.CBI	2	3.CBI	4	3.00	-0.06339	0.07093	946	
Treatment_grou*month	3.CBI	2	4.Neither	1	3.00	0.009359	0.1230	946	
Treatment_grou*month	3.CBI	2	4.Neither	2	3.00	-0.2042	0.1292	946	
Treatment_grou*month	3.CBI	2	4.Neither	3	3.00	-0.3247	0.1300	946	
Treatment_grou*month	3.CBI	2	4.Neither	4	3.00	-0.4750	0.1318	946	
Treatment_grou*month	3.CBI	3	3.CBI	4	3.00	0.04557	0.05768	946	
Treatment_grou*month	3.CBI	3	4.Neither	1	3.00	0.1183	0.1236	946	
Treatment_grou*month	3.CBI	3	4.Neither	2	3.00	-0.09527	0.1297	946	
Treatment_grou*month	3.CBI	3	4.Neither	3	3.00	-0.2157	0.1305	946	
Treatment_grou*month	3.CBI	3	4.Neither	4	3.00	-0.3660	0.1323	946	
Treatment_grou*month	3.CBI	4	4.Neither	1	3.00	0.07275	0.1255	946	
Treatment_grou*month	3.CBI	4	4.Neither	2	3.00	-0.1408	0.1316	946	
Treatment_grou*month	3.CBI	4	4.Neither	3	3.00	-0.2613	0.1324	946	
Treatment_grou*month	3.CBI	4	4.Neither	4	3.00	-0.4116	0.1342	946	
Treatment_grou*month	4.Neither	1	4.Neither	2	3.00	-0.2136	0.06750	946	
Treatment_grou*month	4.Neither	1	4.Neither	3	3.00	-0.3340	0.08672	946	
Treatment_grou*month	4.Neither	1	4.Neither	4	3.00	-0.4843	0.09184	946	
Treatment_grou*month	4.Neither	2	4.Neither	3	3.00	-0.1204	0.06963	946	
Treatment_grou*month	4.Neither	2	4.Neither	4	3.00	-0.2707	0.07781	946	
Treatment_grou*month	4.Neither	3	4.Neither	4	3.00	-0.1503	0.06291	946	

Differences of Least Squares Means	
Effect	Treatment_group	month	_Treatment_group	_month	t Value	Pr > |t|	Alpha	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	2	-0.88	0.3764	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	3	-0.38	0.7045	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	4	-0.49	0.6251	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	1	1.95	0.0519	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	2	0.43	0.6694	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	3	-0.32	0.7461	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	4	-0.03	0.9726	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	1	1.62	0.1060	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	2	0.26	0.7917	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	3	1.14	0.2553	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	4	0.66	0.5067	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	1	0.54	0.5881	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	2	-1.61	0.1079	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	3	-2.47	0.0135	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	4	-2.84	0.0045	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	3	0.38	0.7023	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	4	0.18	0.8585	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	1	2.31	0.0211	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	2	0.85	0.3942	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	3	0.13	0.8949	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	4	0.40	0.6881	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	1	2.00	0.0457	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	2	0.70	0.4849	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	3	1.53	0.1272	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	4	1.07	0.2858	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	1	0.99	0.3222	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	2	-1.07	0.2853	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	3	-1.90	0.0583	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	4	-2.25	0.0244	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	1.Naltrexone + CBI	4	-0.19	0.8459	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	1	2.07	0.0388	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	2	0.64	0.5194	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	3	-0.06	0.9491	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	4	0.20	0.8377	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	1	1.76	0.0781	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	2	0.49	0.6227	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	3	1.31	0.1901	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	4	0.86	0.3884	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	1	0.76	0.4447	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	2	-1.26	0.2095	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	3	-2.07	0.0387	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	4	-2.42	0.0156	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	1	2.12	0.0346	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	2	0.72	0.4707	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	3	0.03	0.9783	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	4	0.29	0.7724	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	1	1.82	0.0694	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	2	0.57	0.5669	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	3	1.37	0.1697	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	4	0.93	0.3504	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	1	0.84	0.3993	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	2	-1.14	0.2565	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	3	-1.93	0.0535	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	4	-2.28	0.0228	0.05	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	2	-2.57	0.0104	0.05	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	3	-3.08	0.0021	0.05	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	4	-2.53	0.0117	0.05	
Treatment_grou*month	2.Naltrexone	1	3.CBI	1	-0.34	0.7355	0.05	
Treatment_grou*month	2.Naltrexone	1	3.CBI	2	-1.56	0.1186	0.05	
Treatment_grou*month	2.Naltrexone	1	3.CBI	3	-0.68	0.4970	0.05	
Treatment_grou*month	2.Naltrexone	1	3.CBI	4	-1.11	0.2681	0.05	
Treatment_grou*month	2.Naltrexone	1	4.Neither	1	-1.43	0.1528	0.05	
Treatment_grou*month	2.Naltrexone	1	4.Neither	2	-3.46	0.0006	0.05	
Treatment_grou*month	2.Naltrexone	1	4.Neither	3	-4.30	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	1	4.Neither	4	-4.64	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	3	-1.33	0.1850	0.05	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	4	-0.74	0.4622	0.05	
Treatment_grou*month	2.Naltrexone	2	3.CBI	1	1.08	0.2784	0.05	
Treatment_grou*month	2.Naltrexone	2	3.CBI	2	-0.15	0.8773	0.05	
Treatment_grou*month	2.Naltrexone	2	3.CBI	3	0.67	0.5017	0.05	
Treatment_grou*month	2.Naltrexone	2	3.CBI	4	0.24	0.8139	0.05	
Treatment_grou*month	2.Naltrexone	2	4.Neither	1	0.07	0.9412	0.05	
Treatment_grou*month	2.Naltrexone	2	4.Neither	2	-1.92	0.0551	0.05	
Treatment_grou*month	2.Naltrexone	2	4.Neither	3	-2.73	0.0064	0.05	
Treatment_grou*month	2.Naltrexone	2	4.Neither	4	-3.08	0.0021	0.05	
Treatment_grou*month	2.Naltrexone	3	2.Naltrexone	4	0.56	0.5758	0.05	
Treatment_grou*month	2.Naltrexone	3	3.CBI	1	1.81	0.0704	0.05	
Treatment_grou*month	2.Naltrexone	3	3.CBI	2	0.55	0.5815	0.05	
Treatment_grou*month	2.Naltrexone	3	3.CBI	3	1.36	0.1736	0.05	
Treatment_grou*month	2.Naltrexone	3	3.CBI	4	0.92	0.3593	0.05	
Treatment_grou*month	2.Naltrexone	3	4.Neither	1	0.82	0.4100	0.05	
Treatment_grou*month	2.Naltrexone	3	4.Neither	2	-1.18	0.2395	0.05	
Treatment_grou*month	2.Naltrexone	3	4.Neither	3	-1.98	0.0476	0.05	
Treatment_grou*month	2.Naltrexone	3	4.Neither	4	-2.33	0.0198	0.05	
Treatment_grou*month	2.Naltrexone	4	3.CBI	1	1.50	0.1340	0.05	
Treatment_grou*month	2.Naltrexone	4	3.CBI	2	0.27	0.7838	0.05	
Treatment_grou*month	2.Naltrexone	4	3.CBI	3	1.08	0.2822	0.05	
Treatment_grou*month	2.Naltrexone	4	3.CBI	4	0.64	0.5204	0.05	
Treatment_grou*month	2.Naltrexone	4	4.Neither	1	0.52	0.6003	0.05	
Treatment_grou*month	2.Naltrexone	4	4.Neither	2	-1.43	0.1517	0.05	
Treatment_grou*month	2.Naltrexone	4	4.Neither	3	-2.23	0.0261	0.05	
Treatment_grou*month	2.Naltrexone	4	4.Neither	4	-2.57	0.0103	0.05	
Treatment_grou*month	3.CBI	1	3.CBI	2	-2.30	0.0219	0.05	
Treatment_grou*month	3.CBI	1	3.CBI	3	-0.54	0.5924	0.05	
Treatment_grou*month	3.CBI	1	3.CBI	4	-1.12	0.2613	0.05	
Treatment_grou*month	3.CBI	1	4.Neither	1	-1.10	0.2735	0.05	
Treatment_grou*month	3.CBI	1	4.Neither	2	-3.15	0.0017	0.05	
Treatment_grou*month	3.CBI	1	4.Neither	3	-4.00	<.0001	0.05	
Treatment_grou*month	3.CBI	1	4.Neither	4	-4.35	<.0001	0.05	
Treatment_grou*month	3.CBI	2	3.CBI	3	1.59	0.1121	0.05	
Treatment_grou*month	3.CBI	2	3.CBI	4	0.67	0.5012	0.05	
Treatment_grou*month	3.CBI	2	4.Neither	1	0.24	0.8106	0.05	
Treatment_grou*month	3.CBI	2	4.Neither	2	-1.77	0.0773	0.05	
Treatment_grou*month	3.CBI	2	4.Neither	3	-2.58	0.0100	0.05	
Treatment_grou*month	3.CBI	2	4.Neither	4	-2.93	0.0034	0.05	
Treatment_grou*month	3.CBI	3	3.CBI	4	-0.90	0.3657	0.05	
Treatment_grou*month	3.CBI	3	4.Neither	1	-0.65	0.5177	0.05	
Treatment_grou*month	3.CBI	3	4.Neither	2	-2.60	0.0095	0.05	
Treatment_grou*month	3.CBI	3	4.Neither	3	-3.40	0.0007	0.05	
Treatment_grou*month	3.CBI	3	4.Neither	4	-3.74	0.0002	0.05	
Treatment_grou*month	3.CBI	4	4.Neither	1	-0.18	0.8571	0.05	
Treatment_grou*month	3.CBI	4	4.Neither	2	-2.11	0.0351	0.05	
Treatment_grou*month	3.CBI	4	4.Neither	3	-2.90	0.0038	0.05	
Treatment_grou*month	3.CBI	4	4.Neither	4	-3.24	0.0013	0.05	
Treatment_grou*month	4.Neither	1	4.Neither	2	-4.10	<.0001	0.05	
Treatment_grou*month	4.Neither	1	4.Neither	3	-4.49	<.0001	0.05	
Treatment_grou*month	4.Neither	1	4.Neither	4	-4.85	<.0001	0.05	
Treatment_grou*month	4.Neither	2	4.Neither	3	-1.65	0.0984	0.05	
Treatment_grou*month	4.Neither	2	4.Neither	4	-2.19	0.0288	0.05	
Treatment_grou*month	4.Neither	3	4.Neither	4	-0.85	0.3977	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	2	0.65	0.5167	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	3	0.49	0.6274	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	4	0.78	0.4359	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	1	3.43	0.0006	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	2	2.43	0.0153	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	3	2.59	0.0097	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	4	2.86	0.0043	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	1	2.92	0.0036	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	2	1.98	0.0485	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	3	1.08	0.2823	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	4	1.43	0.1545	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	1	2.08	0.0378	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	2	0.29	0.7735	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	3	-0.66	0.5095	0.05	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	4	-1.81	0.0700	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	3	-0.04	0.9669	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	4	0.36	0.7189	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	1	2.95	0.0032	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	2	2.01	0.0449	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	3	2.18	0.0293	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	4	2.45	0.0143	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	1	2.44	0.0147	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	2	1.55	0.1210	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	3	0.68	0.4960	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	4	1.03	0.3048	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	1	1.65	0.0997	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	2	-0.07	0.9423	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	3	-0.99	0.3213	0.05	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	4	-2.11	0.0349	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	1.Naltrexone + CBI	4	0.50	0.6206	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	1	2.92	0.0035	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	2	2.00	0.0461	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	3	2.17	0.0302	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	4	2.44	0.0149	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	1	2.42	0.0156	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	2	1.55	0.1220	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	3	0.69	0.4894	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	4	1.03	0.3025	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	1	1.64	0.1011	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	2	-0.05	0.9601	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	3	-0.96	0.3396	0.05	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	4	-2.06	0.0398	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	1	2.63	0.0088	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	2	1.73	0.0834	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	3	1.91	0.0562	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	4	2.18	0.0295	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	1	2.13	0.0338	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	2	1.28	0.1996	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	3	0.45	0.6554	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	4	0.78	0.4337	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	1	1.37	0.1705	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	2	-0.27	0.7847	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	3	-1.16	0.2463	0.05	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	4	-2.24	0.0253	0.05	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	2	-1.46	0.1444	0.05	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	3	-0.77	0.4400	0.05	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	4	-0.32	0.7516	0.05	
Treatment_grou*month	2.Naltrexone	1	3.CBI	1	-0.62	0.5377	0.05	
Treatment_grou*month	2.Naltrexone	1	3.CBI	2	-1.39	0.1648	0.05	
Treatment_grou*month	2.Naltrexone	1	3.CBI	3	-2.27	0.0237	0.05	
Treatment_grou*month	2.Naltrexone	1	3.CBI	4	-1.87	0.0622	0.05	
Treatment_grou*month	2.Naltrexone	1	4.Neither	1	-1.33	0.1833	0.05	
Treatment_grou*month	2.Naltrexone	1	4.Neither	2	-2.94	0.0034	0.05	
Treatment_grou*month	2.Naltrexone	1	4.Neither	3	-3.86	0.0001	0.05	
Treatment_grou*month	2.Naltrexone	1	4.Neither	4	-4.96	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	3	0.41	0.6800	0.05	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	4	0.87	0.3861	0.05	
Treatment_grou*month	2.Naltrexone	2	3.CBI	1	0.27	0.7864	0.05	
Treatment_grou*month	2.Naltrexone	2	3.CBI	2	-0.51	0.6125	0.05	
Treatment_grou*month	2.Naltrexone	2	3.CBI	3	-1.35	0.1778	0.05	
Treatment_grou*month	2.Naltrexone	2	3.CBI	4	-0.98	0.3268	0.05	
Treatment_grou*month	2.Naltrexone	2	4.Neither	1	-0.44	0.6606	0.05	
Treatment_grou*month	2.Naltrexone	2	4.Neither	2	-2.03	0.0431	0.05	
Treatment_grou*month	2.Naltrexone	2	4.Neither	3	-2.91	0.0037	0.05	
Treatment_grou*month	2.Naltrexone	2	4.Neither	4	-3.98	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	3	2.Naltrexone	4	0.58	0.5652	0.05	
Treatment_grou*month	2.Naltrexone	3	3.CBI	1	0.01	0.9912	0.05	
Treatment_grou*month	2.Naltrexone	3	3.CBI	2	-0.73	0.4650	0.05	
Treatment_grou*month	2.Naltrexone	3	3.CBI	3	-1.54	0.1228	0.05	
Treatment_grou*month	2.Naltrexone	3	3.CBI	4	-1.19	0.2356	0.05	
Treatment_grou*month	2.Naltrexone	3	4.Neither	1	-0.67	0.5042	0.05	
Treatment_grou*month	2.Naltrexone	3	4.Neither	2	-2.20	0.0283	0.05	
Treatment_grou*month	2.Naltrexone	3	4.Neither	3	-3.06	0.0023	0.05	
Treatment_grou*month	2.Naltrexone	3	4.Neither	4	-4.10	<.0001	0.05	
Treatment_grou*month	2.Naltrexone	4	3.CBI	1	-0.31	0.7556	0.05	
Treatment_grou*month	2.Naltrexone	4	3.CBI	2	-1.03	0.3040	0.05	
Treatment_grou*month	2.Naltrexone	4	3.CBI	3	-1.83	0.0680	0.05	
Treatment_grou*month	2.Naltrexone	4	3.CBI	4	-1.47	0.1414	0.05	
Treatment_grou*month	2.Naltrexone	4	4.Neither	1	-0.97	0.3324	0.05	
Treatment_grou*month	2.Naltrexone	4	4.Neither	2	-2.46	0.0140	0.05	
Treatment_grou*month	2.Naltrexone	4	4.Neither	3	-3.31	0.0010	0.05	
Treatment_grou*month	2.Naltrexone	4	4.Neither	4	-4.33	<.0001	0.05	
Treatment_grou*month	3.CBI	1	3.CBI	2	-1.54	0.1230	0.05	
Treatment_grou*month	3.CBI	1	3.CBI	3	-2.56	0.0106	0.05	
Treatment_grou*month	3.CBI	1	3.CBI	4	-1.89	0.0591	0.05	
Treatment_grou*month	3.CBI	1	4.Neither	1	-0.76	0.4476	0.05	
Treatment_grou*month	3.CBI	1	4.Neither	2	-2.44	0.0147	0.05	
Treatment_grou*month	3.CBI	1	4.Neither	3	-3.39	0.0007	0.05	
Treatment_grou*month	3.CBI	1	4.Neither	4	-4.53	<.0001	0.05	
Treatment_grou*month	3.CBI	2	3.CBI	3	-1.71	0.0885	0.05	
Treatment_grou*month	3.CBI	2	3.CBI	4	-0.89	0.3717	0.05	
Treatment_grou*month	3.CBI	2	4.Neither	1	0.08	0.9394	0.05	
Treatment_grou*month	3.CBI	2	4.Neither	2	-1.58	0.1142	0.05	
Treatment_grou*month	3.CBI	2	4.Neither	3	-2.50	0.0127	0.05	
Treatment_grou*month	3.CBI	2	4.Neither	4	-3.60	0.0003	0.05	
Treatment_grou*month	3.CBI	3	3.CBI	4	0.79	0.4297	0.05	
Treatment_grou*month	3.CBI	3	4.Neither	1	0.96	0.3386	0.05	
Treatment_grou*month	3.CBI	3	4.Neither	2	-0.73	0.4629	0.05	
Treatment_grou*month	3.CBI	3	4.Neither	3	-1.65	0.0988	0.05	
Treatment_grou*month	3.CBI	3	4.Neither	4	-2.77	0.0058	0.05	
Treatment_grou*month	3.CBI	4	4.Neither	1	0.58	0.5624	0.05	
Treatment_grou*month	3.CBI	4	4.Neither	2	-1.07	0.2848	0.05	
Treatment_grou*month	3.CBI	4	4.Neither	3	-1.97	0.0488	0.05	
Treatment_grou*month	3.CBI	4	4.Neither	4	-3.07	0.0022	0.05	
Treatment_grou*month	4.Neither	1	4.Neither	2	-3.16	0.0016	0.05	
Treatment_grou*month	4.Neither	1	4.Neither	3	-3.85	0.0001	0.05	
Treatment_grou*month	4.Neither	1	4.Neither	4	-5.27	<.0001	0.05	
Treatment_grou*month	4.Neither	2	4.Neither	3	-1.73	0.0840	0.05	
Treatment_grou*month	4.Neither	2	4.Neither	4	-3.48	0.0005	0.05	
Treatment_grou*month	4.Neither	3	4.Neither	4	-2.39	0.0171	0.05	

Differences of Least Squares Means	
Effect	Treatment_group	month	_Treatment_group	_month	Lower	Upper	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	2	-0.1032	0.03904	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	3	-0.1095	0.07402	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	4	-0.1228	0.07384	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	1	-0.00105	0.2515	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	2	-0.1048	0.1631	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	3	-0.1584	0.1135	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	4	-0.1405	0.1357	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	1	-0.02203	0.2289	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	2	-0.1156	0.1515	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	3	-0.05660	0.2129	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	4	-0.09125	0.1846	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	1	-0.08951	0.1578	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	2	-0.2377	0.02352	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	3	-0.2982	-0.03440	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	4	-0.3267	-0.05994	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	3	-0.05920	0.08785	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	4	-0.07577	0.09091	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	1	0.02365	0.2909	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	2	-0.07972	0.2021	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	3	-0.1332	0.1524	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	4	-0.1152	0.1745	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	1	0.002623	0.2683	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	2	-0.09050	0.1906	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	3	-0.03146	0.2519	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	4	-0.06595	0.2235	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	1	-0.06496	0.1974	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	2	-0.2128	0.06271	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	3	-0.2732	0.004722	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	4	-0.3017	-0.02089	
Treatment_grou*month	1.Naltrexone + CBI	3	1.Naltrexone + CBI	4	-0.07493	0.06142	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	1	0.007377	0.2786	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	2	-0.09589	0.1897	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	3	-0.1494	0.1399	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	4	-0.1313	0.1620	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	1	-0.01366	0.2560	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	2	-0.1067	0.1781	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	3	-0.04762	0.2394	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	4	-0.08208	0.2109	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	1	-0.08126	0.1850	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	2	-0.2290	0.05027	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	3	-0.2894	-0.00773	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	4	-0.3178	-0.03336	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	1	0.01088	0.2886	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	2	-0.09223	0.1995	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	3	-0.1457	0.1497	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	4	-0.1276	0.1717	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	1	-0.01017	0.2660	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	2	-0.1030	0.1880	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	3	-0.04394	0.2492	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	4	-0.07834	0.2207	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	1	-0.07782	0.1951	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	2	-0.2254	0.06018	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	3	-0.2857	0.002155	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	4	-0.3142	-0.02351	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	2	-0.1695	-0.02268	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	3	-0.2417	-0.05362	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	4	-0.2269	-0.02845	
Treatment_grou*month	2.Naltrexone	1	3.CBI	1	-0.1485	0.1049	
Treatment_grou*month	2.Naltrexone	1	3.CBI	2	-0.2420	0.02750	
Treatment_grou*month	2.Naltrexone	1	3.CBI	3	-0.1830	0.08888	
Treatment_grou*month	2.Naltrexone	1	3.CBI	4	-0.2176	0.06055	
Treatment_grou*month	2.Naltrexone	1	4.Neither	1	-0.2160	0.03385	
Treatment_grou*month	2.Naltrexone	1	4.Neither	2	-0.3641	-0.1005	
Treatment_grou*month	2.Naltrexone	1	4.Neither	3	-0.4246	-0.1584	
Treatment_grou*month	2.Naltrexone	1	4.Neither	4	-0.4532	-0.1840	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	3	-0.1279	0.02473	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	4	-0.1158	0.05267	
Treatment_grou*month	2.Naltrexone	2	3.CBI	1	-0.06012	0.2086	
Treatment_grou*month	2.Naltrexone	2	3.CBI	2	-0.1532	0.1308	
Treatment_grou*month	2.Naltrexone	2	3.CBI	3	-0.09411	0.1921	
Treatment_grou*month	2.Naltrexone	2	3.CBI	4	-0.1286	0.1636	
Treatment_grou*month	2.Naltrexone	2	4.Neither	1	-0.1277	0.1377	
Treatment_grou*month	2.Naltrexone	2	4.Neither	2	-0.2755	0.002969	
Treatment_grou*month	2.Naltrexone	2	4.Neither	3	-0.3358	-0.05503	
Treatment_grou*month	2.Naltrexone	2	4.Neither	4	-0.3643	-0.08065	
Treatment_grou*month	2.Naltrexone	3	2.Naltrexone	4	-0.05018	0.09022	
Treatment_grou*month	2.Naltrexone	3	3.CBI	1	-0.01051	0.2622	
Treatment_grou*month	2.Naltrexone	3	3.CBI	2	-0.1034	0.1843	
Treatment_grou*month	2.Naltrexone	3	3.CBI	3	-0.04438	0.2456	
Treatment_grou*month	2.Naltrexone	3	3.CBI	4	-0.07880	0.2171	
Treatment_grou*month	2.Naltrexone	3	4.Neither	1	-0.07813	0.1913	
Treatment_grou*month	2.Naltrexone	3	4.Neither	2	-0.2258	0.05648	
Treatment_grou*month	2.Naltrexone	3	4.Neither	3	-0.2861	-0.00153	
Treatment_grou*month	2.Naltrexone	3	4.Neither	4	-0.3146	-0.02718	
Treatment_grou*month	2.Naltrexone	4	3.CBI	1	-0.03266	0.2443	
Treatment_grou*month	2.Naltrexone	4	3.CBI	2	-0.1255	0.1663	
Treatment_grou*month	2.Naltrexone	4	3.CBI	3	-0.06641	0.2276	
Treatment_grou*month	2.Naltrexone	4	3.CBI	4	-0.1008	0.1990	
Treatment_grou*month	2.Naltrexone	4	4.Neither	1	-0.1003	0.1734	
Treatment_grou*month	2.Naltrexone	4	4.Neither	2	-0.2479	0.03852	
Treatment_grou*month	2.Naltrexone	4	4.Neither	3	-0.3082	-0.01951	
Treatment_grou*month	2.Naltrexone	4	4.Neither	4	-0.3366	-0.04517	
Treatment_grou*month	3.CBI	1	3.CBI	2	-0.1585	-0.01240	
Treatment_grou*month	3.CBI	1	3.CBI	3	-0.1178	0.06729	
Treatment_grou*month	3.CBI	1	3.CBI	4	-0.1558	0.04232	
Treatment_grou*month	3.CBI	1	4.Neither	1	-0.1934	0.05482	
Treatment_grou*month	3.CBI	1	4.Neither	2	-0.3415	-0.07948	
Treatment_grou*month	3.CBI	1	4.Neither	3	-0.4020	-0.1374	
Treatment_grou*month	3.CBI	1	4.Neither	4	-0.4306	-0.1629	
Treatment_grou*month	3.CBI	2	3.CBI	3	-0.01408	0.1345	
Treatment_grou*month	3.CBI	2	3.CBI	4	-0.05503	0.1125	
Treatment_grou*month	3.CBI	2	4.Neither	1	-0.1161	0.1484	
Treatment_grou*month	3.CBI	2	4.Neither	2	-0.2639	0.01374	
Treatment_grou*month	3.CBI	2	4.Neither	3	-0.3243	-0.04425	
Treatment_grou*month	3.CBI	2	4.Neither	4	-0.3527	-0.06987	
Treatment_grou*month	3.CBI	3	3.CBI	4	-0.09974	0.03678	
Treatment_grou*month	3.CBI	3	4.Neither	1	-0.1775	0.08948	
Treatment_grou*month	3.CBI	3	4.Neither	2	-0.3252	-0.04528	
Treatment_grou*month	3.CBI	3	4.Neither	3	-0.3856	-0.1033	
Treatment_grou*month	3.CBI	3	4.Neither	4	-0.4141	-0.1289	
Treatment_grou*month	3.CBI	4	4.Neither	1	-0.1493	0.1242	
Treatment_grou*month	3.CBI	4	4.Neither	2	-0.2968	-0.01075	
Treatment_grou*month	3.CBI	4	4.Neither	3	-0.3572	-0.06878	
Treatment_grou*month	3.CBI	4	4.Neither	4	-0.3856	-0.09444	
Treatment_grou*month	4.Neither	1	4.Neither	2	-0.2088	-0.07370	
Treatment_grou*month	4.Neither	1	4.Neither	3	-0.2880	-0.1128	
Treatment_grou*month	4.Neither	1	4.Neither	4	-0.3194	-0.1355	
Treatment_grou*month	4.Neither	2	4.Neither	3	-0.1294	0.01102	
Treatment_grou*month	4.Neither	2	4.Neither	4	-0.1635	-0.00897	
Treatment_grou*month	4.Neither	3	4.Neither	4	-0.08980	0.03569	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	2	-0.09279	0.1844	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	3	-0.1308	0.2168	
Treatment_grou*month	1.Naltrexone + CBI	1	1.Naltrexone + CBI	4	-0.1111	0.2576	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	1	0.1758	0.6473	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	2	0.05877	0.5528	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	3	0.08207	0.5935	
Treatment_grou*month	1.Naltrexone + CBI	1	2.Naltrexone	4	0.1193	0.6401	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	1	0.1112	0.5672	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	2	0.001558	0.4797	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	3	-0.1085	0.3719	
Treatment_grou*month	1.Naltrexone + CBI	1	3.CBI	4	-0.06684	0.4213	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	1	0.01415	0.4858	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	2	-0.2118	0.2846	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	3	-0.3339	0.1659	
Treatment_grou*month	1.Naltrexone + CBI	1	4.Neither	4	-0.4878	0.01914	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	3	-0.1356	0.1300	
Treatment_grou*month	1.Naltrexone + CBI	2	1.Naltrexone + CBI	4	-0.1220	0.1768	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	1	0.1227	0.6088	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	2	0.005936	0.5140	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	3	0.02948	0.5545	
Treatment_grou*month	1.Naltrexone + CBI	2	2.Naltrexone	4	0.06687	0.6010	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	1	0.05780	0.5290	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	2	-0.05150	0.4411	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	3	-0.1615	0.3332	
Treatment_grou*month	1.Naltrexone + CBI	2	3.CBI	4	-0.1198	0.3826	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	1	-0.03900	0.4473	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	2	-0.2646	0.2458	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	3	-0.3867	0.1270	
Treatment_grou*month	1.Naltrexone + CBI	2	4.Neither	4	-0.5405	-0.01985	
Treatment_grou*month	1.Naltrexone + CBI	3	1.Naltrexone + CBI	4	-0.08954	0.1500	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	1	0.1212	0.6159	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	2	0.004605	0.5209	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	3	0.02828	0.5613	
Treatment_grou*month	1.Naltrexone + CBI	3	2.Naltrexone	4	0.06573	0.6077	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	1	0.05615	0.5362	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	2	-0.05296	0.4482	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	3	-0.1630	0.3403	
Treatment_grou*month	1.Naltrexone + CBI	3	3.CBI	4	-0.1211	0.3896	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	1	-0.04051	0.4545	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	2	-0.2659	0.2527	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	3	-0.3879	0.1339	
Treatment_grou*month	1.Naltrexone + CBI	3	4.Neither	4	-0.5417	-0.01299	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	1	0.08554	0.5911	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	2	-0.03080	0.4959	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	3	-0.00696	0.5361	
Treatment_grou*month	1.Naltrexone + CBI	4	2.Naltrexone	4	0.03058	0.5825	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	1	0.02036	0.5116	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	2	-0.08851	0.4233	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	3	-0.1985	0.3154	
Treatment_grou*month	1.Naltrexone + CBI	4	3.CBI	4	-0.1566	0.3646	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	1	-0.07613	0.4297	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	2	-0.3013	0.2276	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	3	-0.4233	0.1088	
Treatment_grou*month	1.Naltrexone + CBI	4	4.Neither	4	-0.5770	-0.03815	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	2	-0.2479	0.03632	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	3	-0.2611	0.1136	
Treatment_grou*month	2.Naltrexone	1	2.Naltrexone	4	-0.2289	0.1653	
Treatment_grou*month	2.Naltrexone	1	3.CBI	1	-0.3027	0.1580	
Treatment_grou*month	2.Naltrexone	1	3.CBI	2	-0.4122	0.07037	
Treatment_grou*month	2.Naltrexone	1	3.CBI	3	-0.5223	-0.03750	
Treatment_grou*month	2.Naltrexone	1	3.CBI	4	-0.4806	0.01195	
Treatment_grou*month	2.Naltrexone	1	4.Neither	1	-0.3996	0.07652	
Treatment_grou*month	2.Naltrexone	1	4.Neither	2	-0.6255	-0.1248	
Treatment_grou*month	2.Naltrexone	1	4.Neither	3	-0.7476	-0.2436	
Treatment_grou*month	2.Naltrexone	1	4.Neither	4	-0.9014	-0.3903	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	3	-0.1203	0.1843	
Treatment_grou*month	2.Naltrexone	2	2.Naltrexone	4	-0.09343	0.2414	
Treatment_grou*month	2.Naltrexone	2	3.CBI	1	-0.2085	0.2753	
Treatment_grou*month	2.Naltrexone	2	3.CBI	2	-0.3175	0.1872	
Treatment_grou*month	2.Naltrexone	2	3.CBI	3	-0.4275	0.07928	
Treatment_grou*month	2.Naltrexone	2	3.CBI	4	-0.3856	0.1286	
Treatment_grou*month	2.Naltrexone	2	4.Neither	1	-0.3051	0.1935	
Treatment_grou*month	2.Naltrexone	2	4.Neither	2	-0.5304	-0.00837	
Treatment_grou*month	2.Naltrexone	2	4.Neither	3	-0.6524	-0.1272	
Treatment_grou*month	2.Naltrexone	2	4.Neither	4	-0.8061	-0.2741	
Treatment_grou*month	2.Naltrexone	3	2.Naltrexone	4	-0.1012	0.1851	
Treatment_grou*month	2.Naltrexone	3	3.CBI	1	-0.2494	0.2522	
Treatment_grou*month	2.Naltrexone	3	3.CBI	2	-0.3580	0.1637	
Treatment_grou*month	2.Naltrexone	3	3.CBI	3	-0.4680	0.05576	
Treatment_grou*month	2.Naltrexone	3	3.CBI	4	-0.4260	0.1049	
Treatment_grou*month	2.Naltrexone	3	4.Neither	1	-0.3457	0.1701	
Treatment_grou*month	2.Naltrexone	3	4.Neither	2	-0.5707	-0.03213	
Treatment_grou*month	2.Naltrexone	3	4.Neither	3	-0.6926	-0.1510	
Treatment_grou*month	2.Naltrexone	3	4.Neither	4	-0.8462	-0.2980	
Treatment_grou*month	2.Naltrexone	4	3.CBI	1	-0.2961	0.2150	
Treatment_grou*month	2.Naltrexone	4	3.CBI	2	-0.4046	0.1263	
Treatment_grou*month	2.Naltrexone	4	3.CBI	3	-0.5145	0.01838	
Treatment_grou*month	2.Naltrexone	4	3.CBI	4	-0.4725	0.06748	
Treatment_grou*month	2.Naltrexone	4	4.Neither	1	-0.3923	0.1328	
Treatment_grou*month	2.Naltrexone	4	4.Neither	2	-0.6171	-0.06963	
Treatment_grou*month	2.Naltrexone	4	4.Neither	3	-0.7390	-0.1885	
Treatment_grou*month	2.Naltrexone	4	4.Neither	4	-0.8926	-0.3356	
Treatment_grou*month	3.CBI	1	3.CBI	2	-0.2239	0.02676	
Treatment_grou*month	3.CBI	1	3.CBI	3	-0.3666	-0.04841	
Treatment_grou*month	3.CBI	1	3.CBI	4	-0.3302	0.006252	
Treatment_grou*month	3.CBI	1	4.Neither	1	-0.3197	0.1412	
Treatment_grou*month	3.CBI	1	4.Neither	2	-0.5459	-0.05969	
Treatment_grou*month	3.CBI	1	4.Neither	3	-0.6680	-0.1784	
Treatment_grou*month	3.CBI	1	4.Neither	4	-0.8220	-0.3251	
Treatment_grou*month	3.CBI	2	3.CBI	3	-0.2344	0.01645	
Treatment_grou*month	3.CBI	2	3.CBI	4	-0.2026	0.07581	
Treatment_grou*month	3.CBI	2	4.Neither	1	-0.2320	0.2508	
Treatment_grou*month	3.CBI	2	4.Neither	2	-0.4577	0.04928	
Treatment_grou*month	3.CBI	2	4.Neither	3	-0.5798	-0.06951	
Treatment_grou*month	3.CBI	2	4.Neither	4	-0.7336	-0.2163	
Treatment_grou*month	3.CBI	3	3.CBI	4	-0.06762	0.1588	
Treatment_grou*month	3.CBI	3	4.Neither	1	-0.1242	0.3608	
Treatment_grou*month	3.CBI	3	4.Neither	2	-0.3498	0.1593	
Treatment_grou*month	3.CBI	3	4.Neither	3	-0.4719	0.04049	
Treatment_grou*month	3.CBI	3	4.Neither	4	-0.6257	-0.1063	
Treatment_grou*month	3.CBI	4	4.Neither	1	-0.1736	0.3191	
Treatment_grou*month	3.CBI	4	4.Neither	2	-0.3991	0.1174	
Treatment_grou*month	3.CBI	4	4.Neither	3	-0.5211	-0.00142	
Treatment_grou*month	3.CBI	4	4.Neither	4	-0.6749	-0.1483	
Treatment_grou*month	4.Neither	1	4.Neither	2	-0.3461	-0.08111	
Treatment_grou*month	4.Neither	1	4.Neither	3	-0.5042	-0.1638	
Treatment_grou*month	4.Neither	1	4.Neither	4	-0.6646	-0.3041	
Treatment_grou*month	4.Neither	2	4.Neither	3	-0.2571	0.01621	
Treatment_grou*month	4.Neither	2	4.Neither	4	-0.4234	-0.1180	
Treatment_grou*month	4.Neither	3	4.Neither	4	-0.2738	-0.02684	

Tests of Effect Slices	
Effect	month	ldpd0	Num DF	Den DF	F Value	Pr > F	
Treatment_grou*month	1	1.00	3	946	0.73	0.5356	
Treatment_grou*month	2	1.00	3	946	0.38	0.7649	
Treatment_grou*month	3	1.00	3	946	2.49	0.0588	
Treatment_grou*month	4	1.00	3	946	1.31	0.2688	
Treatment_grou*month	1	2.00	3	946	1.67	0.1720	
Treatment_grou*month	2	2.00	3	946	1.55	0.1999	
Treatment_grou*month	3	2.00	3	946	3.95	0.0081	
Treatment_grou*month	4	2.00	3	946	4.04	0.0072	
Treatment_grou*month	1	3.00	3	946	4.54	0.0036	
Treatment_grou*month	2	3.00	3	946	2.20	0.0864	
Treatment_grou*month	3	3.00	3	946	3.31	0.0197	
Treatment_grou*month	4	3.00	3	946	6.62	0.0002