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["Research Project - Theodore Tellides (Hopkins High School, visiting student at Yale University, August 2018)"]
[]
["Aorta Calculator based on published data:"]
["Wolak A, Gransar H, Thomson LE, Friedman JD, Hachamovitch R, Gutstein A, Shaw LJ, Polk D, Wong ND, Saouaf R, Hayes SW, Rozanski A, Slomka PJ, Germano G, Berman DS. "]
["Aortic size assessment by noncontrast cardiac computed tomography: normal limits by age, gender, and body surface area."]
[" JACC Cardiovasc Imaging. 2008;1:200-209. "]
[]
["Aorta measured by CT scan in 4,039 asymptomatic, low-risk adult subjects. Excluded outliers and those with hypertension, diabetes, and/or smoking."]
["Ascending aorta: 2,952 (1,147 female and 1,805 male) subjects and descending thoracic aorta: 1,931 (736 female and 1,195 male) subjects"]
["Overall mean+/-SD is 33+/-4 mm for ascending and 24+/-3 mm for descending thoracic aorta (upper limits 41 and 30 mm, respectively)"]
["Female: mean+/-SD is 31.4+/-3.2 mm for ascending and 22.6+/-2.2 mm for descending thoracic aorta  (upper limits 37.4 and 27.0 mm, respectively)"]
["Male: mean+/-SD is 33.5+/-3.6 mm for ascending and 25.1+/-2.5 mm for descending thoracic aorta  (upper limits 40.7 and 30.1 mm, respectively)"]
[]
["Published results for Expected Diameter and SD are shown in tables below by  age, sex, and BSA for ascending and descending thoracic aortas"]
["Expected diameter of ascending and descending thoracic aortas use published regression equations derived from nomograms"]
["SD of ascending and descending thoracic aorta diameters obtained from published tables (except for uncommon groups with <6 subjects where SD was not calculated and overall female or overall male SD was used)"]
[]
["Expected Ascending Aorta Diameter (mm)",{"$nulls":4},"Ascending Aorta SD (mm)"]
["Sex","Age","Mean",null,null,"Sex","Age","BSA","SD","Sex","Age","BSA","SD","Sex","Age","BSA","SD","Sex","Age","BSA","SD"]
["Female","<45","y=4.0*BSA+22.3",null,null,"Female","<45","<1.70",2.7,"Female","55-64","<1.70",2.9,"Male","<45","<1.70",2.2000000000000002,"Male","55-64","<1.70",2.4]
[null,"45-54","y=7.0*BSA+18.7",null,null,null,"<45","1.70-1.89",2.2000000000000002,null,"55-64","1.70-1.89",2.6,null,"<45","1.70-1.89",3.1,null,"55-64","1.70-1.89",3.1]
[null,"55-64","y=5.34*BSA+22.7",null,null,null,"<45","1.90-2.09",2.6,null,"55-64","1.90-2.09",3,null,"<45","1.90-2.09",2.7,null,"55-64","1.90-2.09",3.3]
[null,"≥65","y=3.9*BSA+26.3",null,null,null,"<45","≥2.10","3.2 (overall)",null,"55-64","≥2.10",3.3,null,"<45","≥2.10",3,null,"55-64","≥2.10",3.5]
["Male","<45","y=5.7*BSA+19.6",null,null,"Female","45-54","<1.70",2.8,"Female","≥65","<1.70",2.5,"Male","45-54","<1.70",3.8,"Male","≥65","<1.70",2.2999999999999998]
[null,"45-54","y=5.7*BSA+21.6",null,null,null,"45-54","1.70-1.89",2.9,null,"≥65","1.70-1.89",2.9,null,"45-54","1.70-1.89",3.2,null,"≥65","1.70-1.89",3]
[null,"55-64","y=6.6*BSA+21.3",null,null,null,"45-54","1.90-2.09",3.2,null,"≥65","1.90-2.09",4.2,null,"45-54","1.90-2.09",3.3,null,"≥65","1.90-2.09",3.2]
[null,"≥65","y=4.3*BSA+27.1",null,null,null,"45-54","≥2.10",3.1,null,"≥65","≥2.10","3.2 (overall)",null,"45-54","≥2.10",3.1,null,"≥65","≥2.10",2.8]
[]
["Expected Descending Aorta Diameter (mm)",{"$nulls":4},"Descending Aorta SD (mm)"]
["Sex","Age","Mean",null,null,"Sex","Age","BSA","SD","Sex","Age","BSA","SD","Sex","Age","BSA","SD","Sex","Age","BSA","SD"]
["Female","<45","y=3.6*BSA+14.5",null,null,"Female","<45","<1.70",1.4,"Female","55-64","<1.70",1.8,"Male","<45","<1.70","2.5 (overall)","Male","55-64","<1.70",1.5]
[null,"45-54","y=4.9*BSA+13.5",null,null,null,"<45","1.70-1.89",1.6,null,"55-64","1.70-1.89",1.9,null,"<45","1.70-1.89",2,null,"55-64","1.70-1.89",1.7]
[null,"55-64","y=4.8*BSA+14.7",null,null,null,"<45","1.90-2.09",1.2,null,"55-64","1.90-2.09",1.9,null,"<45","1.90-2.09",1.7,null,"55-64","1.90-2.09",2]
[null,"≥65","y=3.7*BSA+17.8",null,null,null,"<45","≥2.10","2.2 (overall)",null,"55-64","≥2.10",3.1,null,"<45","≥2.10",2,null,"55-64","≥2.10",2.2000000000000002]
["Male","<45","y=4.4*BSA+14.5",null,null,"Female","45-54","<1.70",1.6,"Female","≥65","<1.70",1.8,"Male","45-54","<1.70",1.1000000000000001,"Male","≥65","<1.70","2.5 (overall)"]
[null,"45-54","y=5.2*BSA+14.1",null,null,null,"45-54","1.70-1.89",1.6,null,"≥65","1.70-1.89",1.4,null,"45-54","1.70-1.89",2,null,"≥65","1.70-1.89",2.8]
[null,"55-64","y=5.8*BSA+14.3",null,null,null,"45-54","1.90-2.09",1.8,null,"≥65","1.90-2.09",1.9,null,"45-54","1.90-2.09",2.2000000000000002,null,"≥65","1.90-2.09",2]
[null,"≥65","y=3.9*BSA+19.5",null,null,null,"45-54","≥2.10",2.2000000000000002,null,"≥65","≥2.10",1.9,null,"45-54","≥2.10",1.9,null,"≥65","≥2.10",2]
[]
["BSA calculation based on:"]
["Du Bois D, Du Bois EF. "]
["A formula to estimate the approximate surface area if height and weight be known. "]
["Arch Intern Medicine. 1916;17:863-871."]
[]
["Aorta definitions"]
["Aorta size defined as aneurysm (>1.5x normal), ectasia (<1.5x normal but >2SD larger than normal), normal (within 2SD of normal), hypoplastic (>2SD smaller than normal)"]
[]
["Aneurysm and Ectasia definitions from:"]
["Johnston KW, Rutherford RB, Tilson MD, Shah DM, Hollier L, Stanley JC. "]
["Suggested standards for reporting on arterial aneurysms."]
["J Vasc Surg. 1991;13:452-8."]
[]
["Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, Eagle KA, Hermann LK, Isselbacher EM, Kazerooni EA, et al. "]
["2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/­STS/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease."]
["Circulation. 2010;121:e266-369."]
[]
["Normal aorta definition from:"]
["Wolak A, Gransar H, Thomson LE, Friedman JD, Hachamovitch R, Gutstein A, Shaw LJ, Polk D, Wong ND, Saouaf R, Hayes SW, Rozanski A, Slomka PJ, Germano G, Berman DS. "]
["Aortic size assessment by noncontrast cardiac computed tomography: normal limits by age, gender, and body surface area."]
[" JACC Cardiovasc Imaging. 2008;1:200-209. "]
[]
["McComb BL, Munden RF, Duan F, Jain AA, Tuite C, Chiles C."]
["Normative reference values of thoracic aortic diameter in American College of Radiology Imaging Network (ACRIN 6654) arm of National Lung Screening Trial."]
["Clin Imaging. 2016;40:936-43."]

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["Subject ID","Age (yr)","Sex (M/F or Male/Female)","Height (in) or","Height (cm)","Weight (lb) or","Weight (kg)","Diameter (cm) or","Diameter (mm)","Actual Diameter Ascending Aorta (mm)","Height (cm)","Weight (kg)","Sex","Predicted Diameter Female <45yr","Predicted Diameter Female 45-54yr","Predicted Diameter Female 55-64yr","Predicted Diameter Female ≥65yr","Predicted Diameter Male <45yr","Predicted Diameter Male 45-54yr","Predicted Diameter Male 55-64yr","Predicted Diameter Male ≥65yr","SD Female <45yr <1.70m2","SD Female <45yr 1.70-1.89m2","SD Female <45yr 1.90-2.09m2","SD Female <45yr ≥2.10m2","SD Female 45-54yr <1.70m2","SD Female 45-54yr 1.70-1.89m2","SD Female 45-54yr 1.90-2.09m2","SD Female 45-54yr ≥2.10m2","SD Female 55-64yr <1.70m2","SD Female 55-64yr 1.70-1.89m2","SD Female 55-64yr 1.90-2.09m2","SD Female 55-64yr ≥2.10m2","SD Female ≥65yr <1.70m2","SD Female ≥65yr 1.70-1.89m2","SD Female ≥65yr 1.90-2.09m2","SD Female ±65yr ≥2.10m2","SD Male <45yr <1.70m2","SD Male <45yr 1.70-1.89m2","SD Male <45yr 1.90-2.09m2","SD Male <45yr ≥2.10m2","SD Male 45-54yr <1.70m2","SD Male 45-54yr 1.70-1.89m2","SD Male 45-54yr 1.90-2.09m2","SD Male 45-54yr ≥2.10m2","SD Male 55-64yr <1.70m2","SD Male 55-64yr 1.70-1.89m2","SD Male 55-64yr 1.90-2.09m2","Male 55-64yr ≥2.10m2","SD Male ≥65yr <1.70m2","SD Male ≥65yr 1.70-1.89m2","SD Male ≥65yr 1.90-2.09m2","SD Male ±65yr ≥2.10m2","SD","Ectasia","Aneurysm","Hypoplastic","BSA (m2)","Expected Normal Diameter of Ascending Aorta (mm)","Fold-Increase over Expected Normal Diameter","Z-score","Assessment"]
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[null,"Yale University Section of Cardiac Surgery Aorta Calculator"]
[]
[null,"Age","Sex","Height",null,"Weight",null,"Ascending Aorta Diameter"]
["ENTER"]
[null,"in years","as M/F   OR   Male/female","as inches","OR    as cm","as lb","OR    as kg","as cm","OR    as mm"]
[]
[]
[null,"BSA","Expected Normal Diameter","Aorta Fold-Increase",null,"Aorta Z-Score",null,"Aorta Diagnosis"]
["CALCULATED",{"$f":"BF2","v":0},{"$f":"BG2/10","v":2.23},{"$f":"BH2","v":0},null,{"$f":"BI2","v":-8.2592592592592595},null,{"$f":"BJ2","v":"Hypoplastic"}]
[null,"m2","cm","(versus expected normal)",null,"(SD from normal)",null,"(aneurysm > 1.5x normal)"]
[{"$nulls":7},"(ectasia > 2SD larger, < 1.5x)"]
[{"$nulls":7},"(normal within 2SD)"]
[{"$nulls":7},"(hypoplastic > 2SD smaller)"]

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["Subject ID","Age (yr)","Sex (M/F or Male/Female)","Height (in) or","Height (cm)","Weight (lb) or","Weight (kg)","Diameter (cm) or","Diameter (mm)","Actual Diameter Descending Aorta (mm)","Height (cm)","Weight (kg)","Sex","Predicted Diameter Female <45yr","Predicted Diameter Female 45-55yr","Predicted Diameter Female 55-65yr","Predicted Diameter Female >65yr","Predicted Diameter Male <45yr","Predicted Diameter Male 45-55yr","Predicted Diameter Male 55-65yr","Predicted Diameter Male >65yr","SD Female <45yr <1.70m2","SD Female <45yr 1.70-1.89m2","SD Female <45yr 1.90-2.09m2","SD Female <45yr ≥2.10m2","SD Female 45-54yr <1.70m2","SD Female 45-54yr 1.70-1.89m2","SD Female 45-54yr 1.90-2.09m2","SD Female 45-54yr ≥2.10m2","SD Female 55-64yr <1.70m2","SD Female 55-64yr 1.70-1.89m2","SD Female 55-64yr 1.90-2.09m2","SD Female 55-64yr ≥2.10m2","SD Female ≥65yr <1.70m2","SD Female ≥65yr 1.70-1.89m2","SD Female ≥65yr 1.90-2.09m2","SD Female ±65yr ≥2.10m2","SD Male <45yr <1.70m2","SD Male <45yr 1.70-1.89m2","SD Male <45yr 1.90-2.09m2","SD Male <45yr ≥2.10m2","SD Male 45-54yr <1.70m2","SD Male 45-54yr 1.70-1.89m2","SD Male 45-54yr 1.90-2.09m2","SD Male 45-54yr ≥2.10m2","SD Male 55-64yr <1.70m2","SD Male 55-64yr 1.70-1.89m2","SD Male 55-64yr 1.90-2.09m2","Male 55-64yr ≥2.10m2","SD Male ≥65yr <1.70m2","SD Male ≥65yr 1.70-1.89m2","SD Male ≥65yr 1.90-2.09m2","SD Male ±65yr ≥2.10m2","SD","Ectasia","Aneurysm","Hypoplastic","BSA (m2)","Expected Normal Diameter of Ascending Aorta (mm)","Fold-Increase over Expected Normal Diameter","Z-score","Assessment"]
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[null,"Yale University Section of Cardiac Surgery Aorta Calculator"]
[]
[null,"Age","Sex","Height",null,"Weight",null,"Descending Aorta Diameter"]
["ENTER"]
[null,"in years","as M/F   OR   Male/female","as inches","OR    as cm","as lb","OR    as kg","as cm","OR    as mm"]
[]
[]
[null,"BSA","Expected Normal Diameter","Aorta Fold-Increase",null,"Aorta Z-Score",null,"Aorta Diagnosis"]
["CALCULATED",{"$f":"BF2","v":0},{"$f":"BG2/10","v":1.45},{"$f":"BH2","v":0},null,{"$f":"BI2","v":-10.357142857142858},null,{"$f":"BJ2","v":"Hypoplastic"}]
[null,"m2","cm","(versus expected normal)",null,"(SD from normal)",null,"(aneurysm > 1.5x normal)"]
[{"$nulls":7},"(ectasia > 2SD larger and < 1.5x)"]
[{"$nulls":7},"(normal within 2SD)"]
[{"$nulls":7},"(hypoplastic > 2SD smaller)"]

{"sheet":"Ascending for Databases","index":3,"n_rows":5,"n_cols":64,"rows_kept":5,"cut":false,"hidden":false,"merged":[]}
["Subject ID","Age (yr)","Sex (M/F or Male/Female)","Height (in) or","Height (cm)","Weight (lb) or","Weight (kg)","Diameter (cm) or","Diameter (mm)","Actual Diameter Ascending Aorta (mm)","Height (cm)","Weight (kg)","Sex","Predicted Diameter Female <45yr","Predicted Diameter Female 45-54yr","Predicted Diameter Female 55-64yr","Predicted Diameter Female ≥65yr","Predicted Diameter Male <45yr","Predicted Diameter Male 45-54yr","Predicted Diameter Male 55-64yr","Predicted Diameter Male ≥65yr","SD Female <45yr <1.70m2","SD Female <45yr 1.70-1.89m2","SD Female <45yr 1.90-2.09m2","SD Female <45yr ≥2.10m2","SD Female 45-54yr <1.70m2","SD Female 45-54yr 1.70-1.89m2","SD Female 45-54yr 1.90-2.09m2","SD Female 45-54yr ≥2.10m2","SD Female 55-64yr <1.70m2","SD Female 55-64yr 1.70-1.89m2","SD Female 55-64yr 1.90-2.09m2","SD Female 55-64yr ≥2.10m2","SD Female ≥65yr <1.70m2","SD Female ≥65yr 1.70-1.89m2","SD Female ≥65yr 1.90-2.09m2","SD Female ±65yr ≥2.10m2","SD Male <45yr <1.70m2","SD Male <45yr 1.70-1.89m2","SD Male <45yr 1.90-2.09m2","SD Male <45yr ≥2.10m2","SD Male 45-54yr <1.70m2","SD Male 45-54yr 1.70-1.89m2","SD Male 45-54yr 1.90-2.09m2","SD Male 45-54yr ≥2.10m2","SD Male 55-64yr <1.70m2","SD Male 55-64yr 1.70-1.89m2","SD Male 55-64yr 1.90-2.09m2","Male 55-64yr ≥2.10m2","SD Male ≥65yr <1.70m2","SD Male ≥65yr 1.70-1.89m2","SD Male ≥65yr 1.90-2.09m2","SD Male ±65yr ≥2.10m2","SD","Ectasia","Aneurysm","Hypoplastic","BSA (m2)","Expected Normal Diameter of Ascending Aorta (mm)","Fold-Increase over Expected Normal Diameter","Z-score","Assessment",null,"Instructions"]
[{"$nulls":9},{"$f":"IF(H2>0,H2*10,I2)","v":0},{"$f":"IF(D2>0,D2*2.54,E2)","v":0},{"$f":"IF(F2>0,F2*0.453592,G2)","v":0},{"$f":"IF(C2=\"M\",1,IF(C2=\"Male\",1,0))","v":0},{"$f":"IF(AND(B2<45,M2=0),4*BF2+22.3,0)","v":22.3},{"$f":"IF(AND(B2>=45,B2<55,M2=0),7*BF2+18.7,0)","v":0},{"$f":"IF(AND(B2>=55,B2<65,M2=0),5.34*BF2+22.7,0)","v":0},{"$f":"IF(AND(B2>=65,M2=0),3.9*BF2+26.3,0)","v":0},{"$f":"IF(AND(B2<45,M2=1),5.7*BF2+19.6,0)","v":0},{"$f":"IF(AND(B2>=45,B2<55,M2=1),5.7*BF2+21.6,0)","v":0},{"$f":"IF(AND(B2>=55,B2<65,M2=1),6.6*BF2+21.3,0)","v":0},{"$f":"IF(AND(B2>=65,M2=1),4.3*BF2+27.1,0)","v":0},{"$f":"IF(AND($M2=0,$B2<45,$BF2<1.7),2.7,0)","v":2.7},{"$f":"IF(AND($M2=0,$B2<45,$BF2>=1.7,$BF2<1.9),2.2,0)","v":0},{"$f":"IF(AND($M2=0,$B2<45,$BF2>=1.9,$BF2<2.1),2.6,0)","v":0},{"$f":"IF(AND($M2=0,$B2<45,$BF2>=2.1),3.2,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=45,$B2<55,$BF2<1.7),2.8,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=45,$B2<55,$BF2>=1.7,$BF2<1.9),2.9,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=45,$B2<55,$BF2>=1.9,$BF2<2.1),3.2,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=45,$B2<55,$BF2>=2.1),3.1,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=55,$B2<65,$BF2<1.7),2.9,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=55,$B2<65,$BF2>=1.7,$BF2<1.9),2.6,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=55,$B2<65,$BF2>=1.9,$BF2<2.1),3,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=55,$B2<65,$BF2>=2.1),3.3,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=65,$BF2<1.7),2.5,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=65,$BF2>=1.7,$BF2<1.9),2.9,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=65,$BF2>=1.9,$BF2<2.1),4.2,0)","v":0},{"$f":"IF(AND($M2=0,$B2>=65,$BF2>=2.1),3.2,0)","v":0},{"$f":"IF(AND($M2=1,$B2<45,$BF2<1.7),2.2,0)","v":0},{"$f":"IF(AND($M2=1,$B2<45,$BF2>=1.7,$BF2<1.9),3.1,0)","v":0},{"$f":"IF(AND($M2=1,$B2<45,$BF2>=1.9,$BF2<2.1),2.7,0)","v":0},{"$f":"IF(AND($M2=1,$B2<45,$BF2>=2.1),3,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=45,$B2<55,$BF2<1.7),3.8,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=45,$B2<55,$BF2>=1.7,$BF2<1.9),3.2,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=45,$B2<55,$BF2>=1.9,$BF2<2.1),3.3,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=45,$B2<55,$BF2>=2.1),3.1,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=55,$B2<65,$BF2<1.7),2.4,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=55,$B2<65,$BF2>=1.7,$BF2<1.9),3.1,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=55,$B2<65,$BF2>=1.9,$BF2<2.1),3.3,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=55,$B2<65,$BF2>=2.1),3.5,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=65,$BF2<1.7),2.3,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=65,$BF2>=1.7,$BF2<1.9),3,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=65,$BF2>=1.9,$BF2<2.1),3.2,0)","v":0},{"$f":"IF(AND($M2=1,$B2>=65,$BF2>=2.1),2.8,0)","v":0},{"$f":"MAX(V2:BA2)","v":2.7},{"$f":"IF(AND($J2>=$BG2+$BB2*2,$J2<$BG2*1.5),1,0)","v":0},{"$f":"IF($J2>=1.5*$BG2,1,0)","v":0},{"$f":"IF($J2<=$BG2-$BB2*2,1,0)","v":1},{"$f":"(K2^0.725)*(L2^0.425)*0.007184","v":0},{"$f":"MAX(N2:U2)","v":22.3},{"$f":"J2/BG2","v":0},{"$f":"(J2-BG2)/BB2","v":-8.2592592592592595},{"$f":"IF($BC2=1,\"Ectasia\",IF($BD2=1,\"Aneurysm\",IF($BE2=1,\"Hypoplastic\",\"Normal\")))","v":"Hypoplastic"},null,"1) Enter or paste data into first 9 columns (subject ID is optional, use either M/F or Male/Female, either inches or cm, either lb or kg, and either cm or mm)"]
[{"$nulls":63},"2) Calculations appear in row of cells with yellow highlighted headings (for multiple subjects  select and drag down the entire box from Column J to BJ outlined by heavy black border)"]
[{"$nulls":63},"3) Calculator uses expected aortic diameter from sex-, age- and BSA-stratified nomograms and SD from sex-, age- and BSA-stratified table (see Notes Worksheet)"]
[{"$nulls":63},"4) The condensed yellow columns from J to BE are for conversion and coding purposes and may be ignored"]

{"sheet":"Descending for Databases","index":4,"n_rows":5,"n_cols":64,"rows_kept":5,"cut":false,"hidden":false,"merged":[]}
["Subject ID","Age (yr)","Sex (M/F or Male/Female)","Height (in) or","Height (cm)","Weight (lb) or","Weight (kg)","Diameter (cm) or","Diameter (mm)","Actual Diameter Descending Aorta (mm)","Height (cm)","Weight (kg)","Sex","Predicted Diameter Female <45yr","Predicted Diameter Female 45-55yr","Predicted Diameter Female 55-65yr","Predicted Diameter Female >65yr","Predicted Diameter Male <45yr","Predicted Diameter Male 45-55yr","Predicted Diameter Male 55-65yr","Predicted Diameter Male >65yr","SD Female <45yr <1.70m2","SD Female <45yr 1.70-1.89m2","SD Female <45yr 1.90-2.09m2","SD Female <45yr ≥2.10m2","SD Female 45-54yr <1.70m2","SD Female 45-54yr 1.70-1.89m2","SD Female 45-54yr 1.90-2.09m2","SD Female 45-54yr ≥2.10m2","SD Female 55-64yr <1.70m2","SD Female 55-64yr 1.70-1.89m2","SD Female 55-64yr 1.90-2.09m2","SD Female 55-64yr ≥2.10m2","SD Female ≥65yr <1.70m2","SD Female ≥65yr 1.70-1.89m2","SD Female ≥65yr 1.90-2.09m2","SD Female ±65yr ≥2.10m2","SD Male <45yr <1.70m2","SD Male <45yr 1.70-1.89m2","SD Male <45yr 1.90-2.09m2","SD Male <45yr ≥2.10m2","SD Male 45-54yr <1.70m2","SD Male 45-54yr 1.70-1.89m2","SD Male 45-54yr 1.90-2.09m2","SD Male 45-54yr ≥2.10m2","SD Male 55-64yr <1.70m2","SD Male 55-64yr 1.70-1.89m2","SD Male 55-64yr 1.90-2.09m2","Male 55-64yr ≥2.10m2","SD Male ≥65yr <1.70m2","SD Male ≥65yr 1.70-1.89m2","SD Male ≥65yr 1.90-2.09m2","SD Male ±65yr ≥2.10m2","SD","Ectasia","Aneurysm","Hypoplastic","BSA (m2)","Expected Normal Diameter of Ascending Aorta (mm)","Fold-Increase over Expected Normal Diameter","Z-score","Assessment",null,"Instructions"]
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[{"$nulls":63},"2) Calculations appear in row of cells with yellow highlighted headings (for multiple subjects  select and drag down the entire box from Column J to BJ outlined by heavy black border)"]
[{"$nulls":63},"3) Calculator uses expected aortic diameter from sex-, age- and BSA-stratified nomograms and SD from sex-, age- and BSA-stratified table (see Notes Worksheet)"]
[{"$nulls":63},"4) The condensed yellow columns from J to BE are for conversion and coding purposes and may be ignored"]