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["Participant No","Age","# of cores in RNA later ","Whole blood tube","Histologic Diagnosis (invasive tumor type)","Histologic grade","Tumor size (cm)","Pathologic Primary Tumor (T)","Pathologic Node Status (pN)","Distant Metastases (M)","Number of Lymph Nodes examined","Number of Lymph Nodes involved","Adjuvant Chemotherapy","Type of Regimen","Adjuvant Endocrine Therapy","Date of primary breast cancer surgery","Type of primary breast cancer surgery","ER (estrogen receptor) status","ER, If POSITIVE, % positivity","PR (progesterone receptor) status","PR, If POSITIVE, % positivity","HER2 status","HER2 IHC","Date of first metastatic recurrence","Current sites of metastatic cancer","Site of biopsy","Mutation","Amplification","Deletion/Insertion","Translocation/Duplication"]
["BR001",66,4,"--","invasive ductal carcinoma","3 (poorly differentiated)","1.1","T1c","pNO","M0",8,0,"Yes","ACT and trastuzumab","No","2011-03-17","axillary node dissection; lumpectomy / partial mastectomy","Negative",0,"Negative",0,"Negative","Unknown","2013-03-29","bone; lymph node","lymph node","TP53 Y220C","CCND3, MYC, BCL2L2, JUN, MYST3","",""]
["BR002",62,2,"--","","","","","","",null,null,"No","n/a","Yes",null,"","Positive",99,"Positive",100,"Negative","2+","2011-02-18","bone; liver; lung; lymph node","liver","BRAF G469A; PTEN loss; TP53 R273C; ARID1A Q878*","","",""]
["BR003",68,2,"--","","","3.4","T2","pN1","M0",6,2,"Yes","dose dense ACT, Herceptin with Arimidex; brief tamoxifen","Yes","2006-07-24","axillary node dissection; mastectomy; sentinel node biopsy","Positive",100,"Positive",0,"Negative","2+","2011-04-01","bone; brain; liver; lung","liver","NF1 splice site 205_247del42; BRIP1 N196S; GATA3 A333fs*20","","",""]
["BR004",48,5,"--","invasive ductal carcinoma","2 (moderately differentiated)","3.8","T3","pN3","M1",2,0,"Yes","Adriamycin and Cytoxan followed by Taxol","Yes","2004-10-19","axillary node dissection; mastectomy; sentinel node biopsy","Positive",80,"Positive",30,"Negative","1+","2007-01-26","bone; liver; lung; lymph node; other","liver","PIK3CA E545K; ESR1 Y537N;","CCND1 amplification; MDM4 amplification; FGF4 amplification; FGF19 amplification; FGF3 amplification","",""]
["BR005",58,2,"--","invasive ductal carcinoma","3 (poorly differentiated)","unknown","","","",null,null,"Yes","dose dense AC followed by Taxol","No","2006-10-17","lumpectomy / partial mastectomy","Negative",0,"Negative",0,"Negative","Unknown","2010-07-15","lymph node","lymph node","PIK3CA E545K; SPEN E103fs*27;","MCL1 amplification;","TP53 C141_V143del; CDKN2A/B loss; SMARCA4 splice site 1119-1_1119insAGCCTGCGCAG",""]
["BR006",51,2,"--","invasive ductal carcinoma","2 (moderately differentiated)","5.5","T4b","pN3","M0",32,31,"Yes","dose dense ACT","Yes","2004-12-21","axillary node dissection; mastectomy; sentinel node biopsy","Positive",null,"Positive",null,"Negative","Unknown","2009-05-26","bone; liver; lymph node","liver","PTEN R130G; ESR1 D538G; MAP2K4 loss; GATA3 l407fs*36+;","TOP1 amplification - equivocal; ARFRP1 amplification; ZNF217 amplification","",""]
["BR007",64,2,"--","invasive ductal carcinoma","","2.1","T2","pN1","M0",13,1,"Yes","CMF","Yes","1988-10-03","axillary node dissection; mastectomy; sentinel node biopsy","Positive",null,"Positive",null,"","","2008-10-17","bone; liver; lung; lymph node","liver","ERBB2 D769Y; MAP3K1 T829fs*10;","","PIK3CA E453_D454del; ESR1 L536_Y537insN;",""]
["BR008",35,2,"--","invasive ductal carcinoma","3 (poorly differentiated)","0.05","T1","pNO","",14,0,"Yes","dose dense AC followed by Taxol","No","2011-05-10","axillary node dissection; mastectomy","Negative",0,"Negative",0,"Negative","1+","2012-11-23","bone; brain; liver; lung","liver","TP53 splice site 783-1G>T; RB1 complex rearrangement; CREBBP truncation","MYC amplification","",""]
["BR009",30,4,"--","invasive ductal carcinoma","3 (poorly differentiated)","7.5","T4d","pN3","M0",31,30,"Yes","dose dense ACT","No","2012-08-20","axillary node dissection; mastectomy","Negative",0,"Negative",0,"Negative","","2013-06-17","lung; lymph node","lymph node","TP53 R248W","EGFR; CCND3","",""]
["BR010",61,3,"--","","","","","","",null,null,"","","",null,"","Positive",null,"Positive",null,"Negative","","2003-03-01","bone; liver; lymph node","liver","","","",""]
["BR011",63,2,"--","","2 (moderately differentiated)","unknown","T1","pN1","",7,2,"Yes","CAF followed by Adriamycin, tamoxifen","Yes",null,"axillary node dissection; lumpectomy / partial mastectomy; sentinel node biopsy","Positive",100,"Positive",90,"Negative","Unknown","2011-11-22","bone; liver","liver","RUNX1 L225fs*12; ARID1A T2105fs*35; BTK R492H; ESR1 Y537S; ATRX splice; MAP3K1 R273fs*27, Q535fs*5","","",""]
["BR012",68,2,"--","mixed lobular ductal carcinoma","","1.7","","","",7,0,"No","n/a","Yes","2001-12-12","axillary node dissection; mastectomy; sentinel node biopsy","Negative",0,"Negative",0,"Negative","Unknown","2013-06-06","lymph node","lymph node","PIK3CA D1017H, G1049R; TP53 S241fs*6; CDH1 V459fs*5;","CDK4","",""]
["BR014",43,2,1,"","","","","","",null,null,"Yes","","","2012-03-15","lumpectomy / partial mastectomy; sentinel node biopsy","Negative",null,"Negative",null,"Negative","","2013-06-05","liver","liver","","","",""]
["BR015",57,"--","--","invasive ductal carcinoma","","5.1","","","",null,13,"Yes","dose dense ACT","Yes","2009-08-06","axillary node dissection; lumpectomy / partial mastectomy","Positive",100,"Negative",0,"Negative","1+",null,"bone; liver","liver","TP53 P27fs*17;","PIC3CA, E545K; FGFR1-equivocal; ZNF703","",""]
["BR016",43,2,"--","invasive ductal carcinoma","2 (moderately differentiated)","4","","","M0",17,6,"Yes","dose sense ACT","Yes","2011-09-26","axillary node dissection; mastectomy","Positive",null,"Positive",null,"Negative","","2013-05-16","liver","liver","","","",""]
["BR017",63,4,"--","invasive ductal carcinoma","3 (poorly differentiated)","","","","",null,null,"No","n/a","Yes",null,"","Positive",100,"Positive",50,"Negative","2+","2012-11-23","bone; breast; liver","breast","","FGFR1 amplification;\nCCND1 amplification;\nMYC amplification;\nEMSY amplification;\nFGF19 amplification;\nFGF4 amplification;;\nFGF3 amplification;\nZNF703 amplification","",""]
["BR019",65,2,"--","invasive ductal carcinoma","3 (poorly differentiated)","","","","",null,null,"Yes","CMF x 6 then high dose chemo","Yes","1995-05-15","mastectomy","Positive",90,"Positive",90,"Negative","Unknown",null,"bone; other","other","","","",""]
["BR024",71,2,1,"invasive ductal carcinoma","2 (moderately differentiated)","2.3","","","",7,1,"Yes","AC x 4","Yes",null,"lumpectomy / partial mastectomy; sentinel node biopsy","Positive",null,"Positive",null,"Negative","","2013-03-01","lung; skin","skin","TP53 Q136;","AKT1 amplification, E17K","",""]
["BR026",39,2,1,"invasive ductal carcinoma","2 (moderately differentiated)","","","","",null,null,"No","","","2011-07-08","axillary node dissection; mastectomy","Positive",null,"Negative",null,"Negative","","2013-10-22","liver","liver","","","",""]
["BR027",45,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","1.8","T1c","pN2a","cM0(i+)",4,0,"No","","Yes","2013-02-20","axillary node dissection; mastectomy; sentinel node biopsy","Positive",5,"Positive",5,"Negative","1+","2013-10-03","brain; other","other","TSC2 T849fs*24; TP53 R306*; RARA RARA-LOC400931 fusion;","","",""]
["BR029",65,2,1,"invasive ductal carcinoma","","","","","",null,null,"No","","No",null,"","Positive",95,"Positive",2,"Negative","3+",null,"breast","breast","ATM E71*; MAP2K4 W291*; GATA2 S438fs*9+; LRP1B R2066fs*54; ","PIK3CA amplification; KIT amplification; KDR amplification; SOX2 amplification; IGF1R amplification; CCND1 amplification; EPHB1 amplification; ESR1 amplification; FGF19 amplification; FGF4 amplification; FGF3 amplification; ZNF amplification - equivocal; MYST3 amplification;","TP53 deletion exons 10-11, R156C;",""]
["BR030",55,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","2","","","",8,0,"No","n/a","No",null,"lumpectomy / partial mastectomy; sentinel node biopsy","Negative",null,"Positive",70,"Positive","2+","2009-10-19","bone; brain; liver","liver","TP53 R248Q; RAD50 E1030_L1031>D*EL;","","",""]
["BR031",36,2,1,"invasive ductal carcinoma","2 (moderately differentiated)","2.3","T2","pN1c","",20,2,"No","","No","2012-11-27","axillary node dissection; mastectomy; sentinel node biopsy","Positive",90,"Positive",1,"Negative","1+","2013-01-23","brain; breast; liver; lung; lymph node","breast","PIK3CA H1047R; PTEN C71Y, loss; ERBB3 E928G; BRCA2 K3326*; ","FGFR2 amplification; CCND amplification; FGF3 amplification; FGF4 amplification; FGF19 amplification;","SUFU deletion exons 9-11; ",""]
["BR032",49,2,1,"","","","","","",null,null,"Yes","dd ACT and anastrozole","Yes","2004-10-01","mastectomy","Positive",null,"",null,"Positive","3+","2011-05-01","bone; lymph node","lymph node","CDK12 rearrangement, exon 14; PAX5 TPM2-PAX5 fusion;","ERBB2 amplification; MDM4 amplification - equivocal; ZNF217 amplification; ","",""]
["BR033",55,1,1,"invasive ductal carcinoma","2 (moderately differentiated)","1.4 x 1.2","T1c","pNO","",1,0,"Yes","","Yes","2008-08-13","lumpectomy / partial mastectomy; sentinel node biopsy","Positive",null,"Positive",null,"Negative","","2013-03-01","bone; lymph node; skin","skin","PTEN T319fs*6; TP53 P98fs*54; MLL2 P1131L;","MYCL1 amplification; CCND1 amplification - equivocal; JUN amplification; FGF19 amplification - equivocal; FGF4 amplification - equivocal; FGF3 amplification - equivocal ","",""]
["BR034",54,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","2.5","","","",null,null,"Yes","dd ACT","Yes","2006-02-01","mastectomy","Positive",90,"Negative",null,"Negative","","2012-02-15","brain; liver; lung","liver","ESR1 Y537N; GATA3 S405fs*42+;","GNAS amplification - equivocal; IGF1R amplification; MYC amplification; ARFRP1 amplification - equivocal; ZNF217 amplification; ","",""]
["BR036",34,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","","T2","pNO","M1",null,null,"","","",null,"","Positive",null,"Positive",null,"Negative","1+",null,"bone; brain","liver","ESR1 Y537S; ARID1A S264*; RAD50 L424fs*7;\n","TOP1 amplification - equivocal; CCND1 amplification - equivocal; MYC amplification; FGF19 amplification - equivocal; FGF4 amplification - equivocal; FGF3 amplification - equivocal;","",""]
["BR038",50,"--","--","","","","","","",null,null,"","","",null,"","Positive",null,"Negative",null,"Negative","",null,"","","","","",""]
["BR039",62,2,"--","","","","","","",null,null,"","","",null,"","Positive",null,"",null,"Negative","",null,"","lymph node","TP53 K120E; NOTCH1 Y967*; CDH1 loss;","","",""]
["BR041",62,2,1,"invasive ductal carcinoma","","2.7","","","",12,12,"No","","Yes",null,"axillary node dissection; mastectomy","Positive",95,"Positive",90,"Negative","","2012-11-15","liver; other","liver","PIK3CA H1047R; PTEN T319fs*1; CDKN2A/B loss; TP53 R175H; APC truncation exon 9; CARD11 S652L - subclonal;","MYCN amplification; SOX2 amplification - equivocal; CCND1 amplification; FGF19 amplification; FGF4 amplification; FGF3 amplification; ","",""]
["BR042",43,2,1,"","","","T2","pN1","M0",null,null,"Yes","Adriamycin and Cytoxan, followed by Taxol.","Yes","2002-01-01","mastectomy","Positive",null,"Positive",null,"Negative","","2012-02-13","bone; brain; liver; lung; lymph node; other","skin","","","",""]
["BR043",75,4,1,"OTHER","1 (well-differentiated)","1.2","T1","pNO","",null,null,"No","","Yes","1997-07-23","axillary node dissection","Positive",30,"Positive",50,"","","2010-09-21","lymph node; other","lymph node","PIK3CA E542K; FGFR2 P253R, Y375C; ERBB2; MITF V99I;","FGFR1 amplification; MYC amplification; MYST3 amplification; ZNF703 amplification","",""]
["BR044",72,2,1,"invasive ductal carcinoma","2 (moderately differentiated)","1.8","","","",null,null,"Yes","Avastin and Letrozole","Yes","2008-08-04","lumpectomy / partial mastectomy","Positive",null,"Positive",null,"Negative","1+","2014-02-10","bone; liver; lung; lymph node","liver","PTEN T319fs*1\n\nTP53 H179Y\n\nESR1 Y537C\n\nLRP1B splice site 3521-1G>T"," EPHB1 amplification- equivocal\n\nARFRP1 amplification \n\n","",""]
["BR045",55,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","2","T2","pNO","",4,0,"","","","2005-05-10","lumpectomy / partial mastectomy; sentinel node biopsy; sentinel node biopsy","Positive",65,"Positive",75,"Negative","","2011-02-16","bone; liver; liver; other","liver","","","",""]
["BR046",46,2,1,"","2 (moderately differentiated)","2.8","T1c","pNO(i-)","M1",null,null,"Yes","AC and Tamoxifen","Yes",null,"lumpectomy / partial mastectomy; mastectomy","Positive",90,"Positive",90,"Negative","2+",null,"liver","liver","PIK3CA H1047R","FGFR1 amplification\nTOP1 amplification- equivocal\nARFRP1 amplification- equivocal\n\nZNF703 amplification\nZNF217 amplification","CDKN2A/B loss",""]
["BR047",60,2,1,"","3 (poorly differentiated)",">5cm","T3","pNO","M1",null,null,"Yes","CAF","",null,"mastectomy","Positive",60,"Positive",60,"Negative","1+","2014-02-25","liver","liver","ERBB1 V777L, V842I; ERBB3 E928G; CDH1 T522fs*35;\n","","",""]
["BR048",51,2,1,"invasive lobular carcinoma","","","","","",null,null,"No","","Yes","2012-01-23","lumpectomy / partial mastectomy; sentinel node biopsy","Positive",null,"Positive",null,"Negative","",null,"lymph node","lymph node","","","",""]
["BR049",49,2,1,"invasive ductal carcinoma","2 (moderately differentiated)","1.1x 12.5 right/ 3.5x 2.5 x 1 left","T2","pN1","",12,3,"Yes","TAC","","2002-09-15","axillary node dissection; lumpectomy / partial mastectomy","Positive",70,"Negative",null,"Negative","1+","2014-02-12","other","other","TP53 M246L; GATA3 G335fs*18","KRAS; FLT3; MDM2; CCND1; CCND2; FGF19; FGF23; FGF3; FGF4; FGF6","",""]
["BR050",35,2,"--","invasive ductal carcinoma","3 (poorly differentiated)","1.5 Right; 4.0 Left","T2","pN2","M0",null,null,"Yes","AC + Taxol","Yes","2012-03-16","mastectomy","Positive",70,"Positive",80,"Negative","","2014-03-07","bone; liver; other","other","PTEN N311fs*4; TP53 H179R; ","EMSY amplification","MAP2K4 loss",""]
["BR051",65,2,"--","","","","","","",null,null,"","","",null,"","Positive",null,"Positive",null,"Negative","","2012-09-25","brain","lymph node","PTEN truncation exon 1\nTP53 E294*","CCNE1 amplification","",""]
["BR052",54,4,1,"","","","","","",null,null,"Yes","Taxol, Herceptin, Pertuzumab","Yes","2013-04-05","lumpectomy / partial mastectomy","Positive",null,"Positive",null,"Positive","","2012-09-08","bone; brain","lymph node","PIK3CA H1047R\nTP53 L348","ERBB2 amplification\nMAP2K2 amplification- equivocal\nMYC amplification- equivocal\nFGF14 amplification- equivocal","",""]
["BR053",75,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","2cm x 2.8cm ","T2","pN1","M0",13,1,"Yes","TC, Neulasta","","2012-10-02","lumpectomy / partial mastectomy","Negative",null,"Negative",null,"Negative","","2013-11-26","bone; skin","lymph node","","","",""]
["BR055",49,"--","--","invasive ductal carcinoma","3 (poorly differentiated)","1.7","T1c","pN1a","M0",8,2,"Yes","AC-Taxol","Yes",null,"lumpectomy / partial mastectomy","Negative",null,"Negative",null,"Negative","","2014-04-24","lymph node; skin","skin","PIK3R1 A331fs*2;\nTP53 R11OP","CCNE1 amplification- equivocal","STK11 loss exon 1 ",""]
["BR056",44,2,1,"invasive ductal carcinoma","","","","","",null,null,"","","",null,"","Positive",null,"Positive",null,"Negative","",null,"liver","liver","","","",""]
["BR057",77,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","","","","",null,null,"No","","Yes",null,"","Positive",90,"Positive",90,"Negative","","2011-09-15","bone; liver","liver","","","",""]
["BR058",62,"--",1,"","","","","","",null,null,"","","",null,"","Positive",95,"Positive",15,"Negative","1+","2013-01-09","lymph node; other","other","PIK3CA E545K- subclonal;\nCDH1 1650fs*13","","",""]
["BR059",51,2,1,"invasive ductal carcinoma","",".35 x .6","T1b","pNO","",null,null,"Yes","Tamoxifen","","2010-09-23","mastectomy","Positive",null,"Positive",null,"Negative","","2014-05-15","bone; liver; lymph node","lymph node","","","",""]
["BR060",63,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","1.4cm","T1c","pNO","",null,null,"No","","Yes","2004-06-02","mastectomy","Positive",null,"Positive",null,"Negative","1+","2006-08-29","lymph node; other","other","BRCA2 T3033fs*29\nJAK2 E1097*","KIT amplification- equivocal\nGNAS amplification\nKRAS amplification\nTOP1 amplification- equivocal\nAURKA amplification\nZNF217 amplification","TP53 loss exons 8-9",""]
["BR061",62,2,1,"","","","","","",null,null,"Yes","Doxorubicin/cyclophosphamide","",null,"mastectomy","Positive",null,"Positive",null,"Negative","","2011-05-11","liver; other","bone","PIK3CA H1047R\nCDH1 D400Y\nLRP1B R590fs*4","CCND1 amplification\nEMSY amplification\nFGF19 amplification\nFGF3 amplification\nFGF4 amplification","",""]
["BR062",47,2,1,"invasive ductal carcinoma","","","","","",null,null,"Yes","Tamoxifen","",null,"","Positive",null,"Positive",null,"Negative","1+","2013-04-13","bone; liver; lymph node","liver","PIK3CA E545K\nTP53 R248G","CCND1 amplification\nMYC amplification\nEMSY amplification\nFGF19 amplification\nFGF3 amplification\nFGF4 amplification","",""]
["BR063",47,2,"--","invasive ductal carcinoma","","2cm","T2","pN1","M0",null,null,"Yes","Docetaxel, Doxorubicin, Cyclophosphamide","","2004-10-15","mastectomy","Positive",null,"Positive",null,"Negative","","2010-06-15","bone; brain; lung; lymph node; other","lymph node","FGFR2 K659E","CCND1 amplification; FGF19 amplification; FGF3 amplification; FGF4 amplification","",""]
["BR064",69,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","2.6 x 2.2 x 2.1cm","T2","pNO","",null,null,"Yes","Taxotene and Cytoxan","Yes","2013-04-29","axillary node dissection; lumpectomy / partial mastectomy","Positive",90,"Negative",null,"Negative","","2014-07-17","bone; liver; lung; lymph node","lung","TP53 H297fs*48","CCNE1 amplification-equivocal; MYC amplification- equivocal","STK11 loss",""]
["BR068",66,2,1,"ductal carcinoma in situ (DCIS)","","","","","",null,null,"Yes","Tamoxifen","",null,"lumpectomy / partial mastectomy","Positive",90,"Positive",30,"","2+","2014-07-25","lung; skin","lung","PTEN N323fs*2; MAP2k4 S240fs*29;","FGFR2 amplfiication; TOP1 amplification; ARFRp1 amplification; ZNF217 amplification","",""]
["BR069",72,2,1,"invasive ductal carcinoma","","","T1c","pNO(i-)","",null,null,"No","","Yes",null,"lumpectomy / partial mastectomy","Positive",95,"Positive",80,"Negative","","2010-10-27","bone; lung; lymph node","lymph node","PIK3CA H1047R","AKT3 amplification; PDGFRB amplification- equivocal; FGFR4 amplfiication; FLT4 amplification; TOP1 amplification- equivocal; IKBKE amplification; MDM2 amplification; MDM4 amplification; ZNF217 amplification- equivocal;","",""]
["BR070",57,2,1,"","","","","","",null,null,"Yes","","",null,"","",null,"",null,"","",null,"bone; lymph node; other","bone","FGFR2 S252W; PIK3CA H1047R; TP53 K132N","GNAS amplification; AURKA amplification; CCND1 amplification; FGF19 amplification; FGF3 amplification; FGF4 amplification;","",""]
["BR071",43,4,1,"invasive ductal carcinoma","3 (poorly differentiated)","","T2","pN2a","",9,9,"Yes","AC + Taxol","Yes",null,"","Positive",90,"Positive",88,"Negative","2+",null,"lymph node","lymph node","PIK3CA V105_E109>3; Sf3B1 K700E","IKBKE amplification; EPHA3 amplification- equivocal;","TP53 splice site 560-1delG",""]
["BR072",44,2,1,"invasive ductal carcinoma","","","T2","pN1","M0",null,null,"Yes","ddAC --> Taxol","","2012-12-15","axillary node dissection; mastectomy","Negative",null,"Negative",null,"Negative","","2014-04-14","bone; liver; lung","liver","TP53 R175H; CTNNB1 A636fs*12;","AKT2 amplification; CCNE1 amplification; MYST3 amplification- equivocal","",""]
["BR073",57,2,1,"invasive lobular carcinoma","","","T2","pN3c","M0",null,28,"Yes","","Yes",null,"axillary node dissection; mastectomy","Positive",70,"Positive",70,"Negative","1+","2014-04-14","liver; lung; lymph node","lymph node","PIK3CA H1047L; RUNX1 Q425fs*66+; CDH1 Q346*; ESR1 D538G","","",""]
["BR074",51,2,1,"","","","T0","pNO","M0",null,null,"Yes","Neoadjuvant- Doxorubicin/Cyclophasphamide/Paclitaxel","","2011-03-31","mastectomy","Negative",null,"",null,"Negative","","2013-10-22","bone; liver; other","liver","PIK3CA C407W; TP53 F109_R110del; PRKDC R1136H- subclonal;","FGF14 amplification;","",""]
["BR075",46,2,1,"invasive ductal carcinoma","","","T2","pN1","M0",null,null,"Yes","","Yes",null,"mastectomy","Positive",20,"Negative",10,"Negative","","2014-08-15","bone; brain; liver; lung","liver","HRAS Q61K- subclonal\nKRAS Q61K\nTP53 G245D","PIK3CA amplification, H1047R","",""]
["BR076",59,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","","T2","","",null,null,"","","",null,"","Positive",null,"Positive",null,"Negative","3+","2013-03-08","bone; liver","liver","PTENQ171;\nVHL F76L;\nCDK12 truncation exon 2;\nTP53 R65fs*58;\nMLL2 E551;\n","ERBB2 amplification;\nERBB3 amplification;\nCCND3 amplification;\nMYC amplification;","RB1 loss exons 7-17",""]
["BR079",57,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","3.3 x 2.8","T2","pN1a","M1",9,2,"Yes","NeoadjuvantTaxotere followed by Adriamycin/Cytoxan","","2013-08-06","mastectomy","Negative",null,"Negative",null,"Negative","","2013-01-04","bone; brain; liver; lung","lung","TP53 W91;","PIK3CA amplification; CCND3 amplification- equivocal; IKBKE amplification- equivocal; SOX2 amplification","",""]
["BR080",56,2,1,"","3 (poorly differentiated)","","T3","pN3","M1",null,null,"No","","",null,"","Positive",90,"Positive",30,"Negative","","2014-07-31","bone; lung","breast","","CCND1 amplification; EMSY amplfiication; FGF19 amplification; FGF3 amplifiation; FGF4 amplification","",""]
["BR081",53,"--",1,"invasive ductal carcinoma","2 (moderately differentiated)","5.4cm","T3","pN2a","M1",5,5,"Yes","TAC","Yes","2013-07-25","mastectomy","Positive",80,"Negative",null,"Negative","Unknown",null,"bone; lymph node; other","other","PIK3CA N345K; ESR1 Y537S; MSH2 E529; ERBB2","CCND1 amplification; FGF19 amplification; FGF3 amplification; FGF4 amplification","",""]
["BR084",51,2,1,"invasive lobular carcinoma","3 (poorly differentiated)","0.1","T1","pNO(i+)","M0",15,0,"Yes","Carbo Gemzar","No","2013-01-30","axillary node dissection; lumpectomy / partial mastectomy","Negative",null,"Negative",null,"Negative","1+","2014-11-13","bone; liver; other","liver","","","",""]
["BR085",39,"--","--","invasive ductal carcinoma","","3.4","T2","pN2","",3,3,"Yes","dose dense AC - taxol -","Yes",null,"lumpectomy / partial mastectomy","Positive",null,"Negative",null,"Negative","","2014-10-21","bone; liver; lung; lymph node","lymph node","","RPTOR amplification\nFGFR1 amplification\nCCND1 amplification\nMYC amplification\nEMSY amplification\nFGF19 amplification\nFGF3 amplification\nFGF4 amplification\nMYST3 amplification\nZNF703 amplification","",""]
["BR087",42,"--",1,"","","","","","",null,null,"","","",null,"mastectomy","Positive",80,"Positive",80,"Negative","",null,"","lymph node","","","",""]
["BR089",79,2,1,"invasive ductal carcinoma","","","","","",14,4,"Yes","CAF chemo","Yes",null,"mastectomy","Positive",null,"Negative",null,"Negative","","2005-03-15","other","skin","PIK3CA E545Q H1047R;\nRUNX1 RW01Q;\nMAP3K1 W560;\nERBB2","","",""]
["BR090",63,3,1,"invasive lobular carcinoma","2 (moderately differentiated)","","","","",null,null,"","","",null,"","Positive",80,"Positive",50,"","1+","2012-07-17","bone; brain; brain","other","PTEN C93fs*18;\nCDH1 D587fs*2;\nESR1 D538G;\nERBB2\n","CCND1 amplification; \nFGFR1 amplification- equivocal;\nMYC amplification;\nEMSY amplification;\nFGF19 amplification;\nFGF3 amplification;\nFGF4 amplification;\nMYST3 amplification;\nZNF703 amplification- equivocal\n","",""]
["BR091",41,2,1,"invasive ductal carcinoma","2 (moderately differentiated)","","","","",null,null,"","","Yes",null,"","Positive",95,"Positive",96,"Positive","2+","2010-01-01","bone; liver","breast","ESR1 Y537C;","CCND1 amplification;\n FGF19 amplification; \nFGF3 amplification; \nFGF4 amplification;","",""]
["BR093",58,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","4","T2","pN1","M0",6,0,"Yes","","Yes","2011-11-30","lumpectomy / partial mastectomy","Positive",100,"Positive",30,"Positive","2+","2015-01-28","lung; other","lung","ATR F926fs*13;\nTP53 H179R;\nESR1 D538G;\n","CCNE1 amplification;","MAP2K4 loss;","RB1 splice site 2107-1G>T"]
["BR095",71,2,"--","","","","","","",null,null,"","","Yes",null,"lumpectomy / partial mastectomy","",null,"",null,"","","2011-10-25","bone; liver; lung","liver","ESR1 D538G;\nERBB2","CCND1 amplification;\nFGFR1 amplification;\nEMSY amplification;\nFGF19 amplification;\nFGF3 amplification;\nFGF4 amplification;\nMYST3 amplification- equivocal;\nZNF703 amplification;","",""]
["BR096",67,2,1,"","","","","","",null,null,"","","",null,"","Positive",null,"Positive",null,"Negative","",null,"bone; liver; lung","liver","PIK3CA Q546R;\nERBB2","CCND1 amplification;\nFGF19 amplification;\nFGF3 amplification;\nFGF4 amplification","",""]
["BR098",50,2,1,"","","","T1c","pN1","",null,null,"Yes","Adriamycin/Cyclophosphamide","",null,"","Negative",null,"Negative",null,"Negative","","2015-03-18","lymph node","lymph node","","","",""]
["BR099",51,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","1.4","","","",null,null,"Yes","neoadjuvant Abraxane, carboplatin, and bevacizumab","","2011-11-30","lumpectomy / partial mastectomy","Negative",null,"Negative",null,"Negative","","2013-07-15","lymph node","lymph node","TP53 G108fs*15","","","ETV6 truncation intron 5 and duplication exons 6-8"]
["BR100",42,2,1,"","","","T3","pN3","M0",19,19,"Yes","neoadjuvant Adriamycin/Cytoxan/Taxol","",null,"mastectomy","Positive",null,"Positive",null,"Negative","","2013-03-15","bone; liver","","PIK3CA *1069fs*1+; ATR ATR-XRCC4 fusio;\nESR1 D538G","CCND1 amplification;SRC amplification;AURKA amplification\nFGF19 amplification;\nFGF4 amplification;\nGNAS amplification;\nMDM2 amplification;\nMYC amplification;\nTOP1 amplification;FGF3 amplification;\nZNF217 amplification","",""]
["BR102",62,"--",1,"invasive ductal carcinoma","3 (poorly differentiated)","","T2","pN1a","",null,null,"Yes","","Yes",null,"mastectomy; sentinel node biopsy","Positive",90,"Negative",null,"Negative","","2015-04-07","breast","breast","","","",""]
["BR103",69,"--","--","","","","","","",null,null,"","","",null,"mastectomy","",null,"",null,"","","2010-09-15","","lung","NOTCH1 L2457V;\nTP53 P151R;ARID2 E71*, S1491*;\nESR1 Y537C;\nGATA3 S411fs*29+;","PIK3CA amplification – equivocal;\nCCND1 amplification;\nKDR amplification – equivocal;\nFGF19 amplification;\nIGF1R amplification;\nSOX2 amplification;\nARFRP1 amplification – equivocal;\nEMSY amplification;\nFGF3 amplification;\nFGF4 amplification;\nZNF703 amplification;","","MLL2 rearrangement exon 35;\n"]
["BR104",61,"--","--","invasive lobular carcinoma","1 (well-differentiated)","","","","",null,null,"Yes","Taxotere and Cyclophosphamide and Abraxane/Cyclophosphamide","","2011-07-12","mastectomy; sentinel node biopsy","Positive",95,"Positive",90,"Negative","","2010-06-01","skin","skin","","","",""]
["BR106",46,2,1,"","","","","","",null,null,"Yes","doxorubicin, cyclophosphamide, docetaxel","",null,"","Negative",null,"Negative",null,"Negative","",null,"bone; brain; liver; liver; lung","liver","TP53 G244S","PIK3CA amplification, E542K;\nMYC amplification","",""]
["BR107",71,2,1,"","","","","","",null,null,"Yes","CAF","Yes",null,"","",null,"",null,"","",null,"","lymph node","","","",""]
["BR108",43,2,1,"","","","","","",null,null,"","","","2013-02-05","lumpectomy / partial mastectomy","",null,"",null,"","","2014-02-07","brain; lung; lymph node; lymph node","lymph node","","","",""]
["BR109",69,"--",1,"","","","","","",null,null,"Yes","","No",null,"lumpectomy / partial mastectomy","Positive",null,"",null,"Negative","",null,"","other","GATA3 P409fs*38+;\n","AURKA amplification;ZNF217 amplification\n","",""]
["BR110",50,2,1,"invasive ductal carcinoma","","","","","",6,25,"","","Yes","2011-05-31","mastectomy; mastectomy","Positive",60,"Positive",10,"Negative","","2013-01-28","lymph node","","","","",""]
["BR111",55,2,1,"invasive ductal carcinoma","","2.6","T2","pNO","",3,0,"Yes","TC","Yes",null,"mastectomy","Positive",null,"Positive",null,"Negative","",null,"liver","liver","PDGFRA P567L;\nTP53 Y126*;\nMAP2K4 R287H;","IGF1R amplification;\nMYC amplification – equivocal;\nMYST3 amplification;","",""]
["BR112",72,2,1,"","","","","","",null,null,"Yes","","","1993-06-15","mastectomy","",null,"",null,"","","2009-06-15","bone; liver","liver","PIK3CA H1047R;\nRUNX1 L98fs*24;\nESR1 Y537S;","","CDH1 splice site 832+2T>C",""]
["BR113",null,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","","","","",null,null,"","","",null,"","Positive",80,"Positive",70,"Negative","","2012-11-14","bone; breast; liver; other","liver","KRAS G12R;\nTP53 R280T;\nMAP2K4 S184L","CCND1 amplification;\nFGF19 amplification;\nFGF4 amplification;\nFGF3 amplification;\n","PTEN loss;\nLRP1B deletion exons 42-77;",""]
["BR115",61,2,1,"invasive ductal carcinoma","3 (poorly differentiated)","1.2","","","",12,5,"Yes","neoadjuvant- carboplatin, docetaxel, trastuzumab, pertuzumab","","2013-06-05","mastectomy; mastectomy","",null,"",null,"","","2013-01-11","bone; liver; lung; lymph node","liver","","","",""]
["BR117",45,2,1,"","","","","","",null,null,"","","",null,"","",null,"",null,"","","2014-11-10","bone; brain; liver","","PIK3CA H1047R;\nTP53 C275Y;\n","ERBB2 amplification;\nLYN amplification;\nMDM4 amplification;\nPIK3C2B amplification;","CDC73 rearrangement exon 7",""]